Table 4.

The genotype frequencies of CYP3A5 and CYP3A4 polymorphisms (n = 251)

Gene/Genotype	Healthy (n = 122)	Patients (n = 129)
CYP3A5*2 (rs28365083)
*1/*1 (G/G)	122 (100%)	129 (100%)
CYP3A5*3 (rs776746)
*1/*1 (T/T)	2 (1.6%)	2 (1.6%)
*3/*3 (C/C)	120 (98.4%)	127 (98.4%)
CYP3A5*4 (rs56411402)
*1/*1 (T/T)	122 (100%)	129 (100%)
CYP3A4*1B (rs2740574)
*1/*1 (T/T)	106 (86.9%)	113 (87.6%)
*1/*1B (T/C)	14 (11.5%)	15 (11.6%)
*1B/*1B (C/C)	2 (1.6%)	1 (0.8%)
CYP3A4*6 (rs4646438)
*1/*1 (–/–)	122 (100%)	129 (100%)
CYP3A4*18 (rs28371759)
*1/*1 (A/A)	122 (100%)	129 (100%)
CYP3A4*22 (rs35599367)
*1/*1 (G/G)	107 (89.2%)	119 (92.2%)
*1/*22 (G/A)	11 (9.2%)	10 (7.8%)
*22/*22 (A/A)	2 (1.6%)	0 (0.0%)
Missing	2	0