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. 2025 Apr 23;23(3):203–211. doi: 10.1007/s12574-025-00689-9

Table 2.

Right atrial strain means and lower limits of normal and 95% confidence intervals by echocardiography strain software in healthy subjects

Strain vendor software TomTec EchoPAC VVI Epsilon
Number of subjects 100 50 (GE scans only) 100 100
RASr (%)
 Mean 41.2 (38.5, 43.0) 35.9 (34.4, 37.3) 44.8 (42.3, 47.3) 38.9 (36.7, 41.0)
 LLN normal 29.6 (26.5, 32.7) 27.0 (24.5, 29.5) 27.6 (23.3, 31.9) 25.5 (21.7, 29.3)
 Intra-reader variability 4.9 2.1 9.6 4.1
 Inter-reader variability 7.4 4.1 10.2 7.0
RAScd (%)
 Mean −25.9 (−27.5, −24.4) −22.9 (−24.2, −21.5) −27.6 (−29.8, −25.4) −24.5 (−26.4, −22.7)
 LLN normal −14.3 (−17.1, −11.5) −14.0 (−16.4 −11.6) −13.2 (-17.0, -9.4) −12.5 (−15.7, −9.3)
 Intra-reader variability 5.1 2.3 11.1 4.1
 Inter-reader variability 7.7 3.8 7.8 7.0
RASct (%)
 Mean −15.3 (−16.2, −14.4) −12.4 (−13.5, −11.3) −17.1 (−18.6, −15.5) −14.3 (−15.2, −13.5)
 LLN normal −10.2 (−11.7, −8.7) −8.0 (−9.9, −6.1) −8.0 (−10.7, −5.3) −9.6 (−11.1, −8.1)
 Intra-reader variability 3.5 1.6 5.8 3.0
 Inter-reader variability 3.2 5.4 7.1 7.6

The mean or lower limits of normal (LLN) and their 95% confidence intervals (95% CI) are presented. Intra- and inter-reader variability is assessed using the standard error of measurement. RASr right atrial reservoir strain, RAScd right atrial conduit strain, RASct right atrial contractile strain, and VVI velocity vector imaging