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. 2025 Jul 1;13(3):683–694. doi: 10.1007/s40487-025-00353-3

Table 3.

Linear mixed effect model for drug plasma trough levels

Covariates Change in ng/mL Confidence interval p-value
Daily dose in mg 1.21 (0.95–1.47) 0.00
Age in years 1.12 (−4.13–6.38) 0.68
Glivec duration in months 0.38 (−0.81–1.57) 0.53
Sex (male) −54.33 (−171.97–63.31) 0.37
Accord −2.64 (−81.46–76.18) 0.95
Amarox 5.49 (−61.49–72.47) 0.87
Sandoz 40.41 (−72.08–152.90) 0.48

In this model, 390 samples for Glivec, 128 for Accord, 144 for Amarox and 57 for Sandoz were used