Table 3.
Linear mixed effect model for drug plasma trough levels
| Covariates | Change in ng/mL | Confidence interval | p-value |
|---|---|---|---|
| Daily dose in mg | 1.21 | (0.95–1.47) | 0.00 |
| Age in years | 1.12 | (−4.13–6.38) | 0.68 |
| Glivec duration in months | 0.38 | (−0.81–1.57) | 0.53 |
| Sex (male) | −54.33 | (−171.97–63.31) | 0.37 |
| Accord | −2.64 | (−81.46–76.18) | 0.95 |
| Amarox | 5.49 | (−61.49–72.47) | 0.87 |
| Sandoz | 40.41 | (−72.08–152.90) | 0.48 |
In this model, 390 samples for Glivec, 128 for Accord, 144 for Amarox and 57 for Sandoz were used