TABLE 5.
OPRM1 genotype comparison results of patients using hydrocodone in the ADR research group.
| SNP Id | Observation subgroup n = 126 (%) | Control subgroup n = 128 (%) | χ2 | P-value | OR (95% CI) |
|---|---|---|---|---|---|
| AA | 71 (56.35) | 49 (38.28) | |||
| AG | 40 (31.75) | 59 (46.09) | |||
| GG | 15 (11.90) | 20 (15.63) | |||
| AG + GG | 55 (43.65) | 79 (61.72) | 11.000 | 0.012* | 1.234 (1.050–1.451) |
| Allelic | |||||
| A | 182 (72.22) | 157 (61.33) | |||
| G | 70 (27.78) | 99 (38.67) | 6.789 | 0.009 | 1.639 (1.129–2.381) |
Note: * indicates calculations based on the AG + GG genotype group compared to AA.