TABLE 6.

Genetic model analysis of the correlation between genetic polymorphism and the incidence of ADRs.

SNP Id	Model	Genotype	OR	95% CI	P-value	AIC
CYP2D6*10 (rs1065852, C>T)	Codominant	CC/CT/TT	1.05	0.92–1.19	0.368	1890.5
	Dominant	CT/TT vs. CC	1.07	0.80–1.43	0.653	1895.0
	Recessive	TT vs. CC/CT	1.02	0.89–1.16	0.718	1898.2
	Overdominant	CT vs. CC/TT	0.98	0.87–1.11	0.489	1900.3
	Allelic	T vs. C	1.04	0.88–1.22	0.323	1893.6
OPRM1 (rs1799971, A>G)	Codominant	AA/AG/GG	1.16	1.02–1.33	0.013	1885.2
	Dominant	AG/GG vs. AA	1.28	1.10–1.48	0.025	1891.3
	Recessive	GG vs. AA/AG	1.12	0.97–1.29	0.068	1889.0
	Overdominant	AG vs. AA/GG	1.05	0.92–1.21	0.199	1887.5
	Allelic	G vs. A	1.34	1.10–1.64	0.032	1892.3
ABCB1(rs1045642, C>T)	Codominant	CC/CT/TT	0.94	0.83–1.08	0.717	1900.1
	Dominant	CT/TT vs. CC	0.85	0.63–1.15	0.288	1903.5
	Recessive	TT vs. CC/CT	1.09	0.94–1.27	0.412	1904.6
	Overdominant	CT vs. CC/TT	1.01	0.88–1.15	0.602	1902.4
	Allelic	T vs. C	0.98	0.78–1.21	0.492	1901.2
CYP3A5*3 (rs776746, A>G)	Codominant	AA/AG/GG	1.08	0.91–1.25	0.312	1898.2
	Dominant	AG/GG vs. AA	1.05	0.85–1.31	0.444	1899.8
	Recessive	GG vs. AA/AG	1.07	0.89–1.27	0.522	1901.5
	Overdominant	AG vs. AA/GG	1.02	0.82–1.19	0.601	1903.3
	Allelic	G vs. A	1.11	0.94–1.31	0.228	1904.1