Table 3:

Adjusted association between qctPPF status and 2-year TFS in pooled cohort stratified by ILD subtype

Cohort (n)	qctPPF(+) (n/%)	HR	95% CI	p
Pooled (442)	204 (46.2)	4.28	2.90–6.31	<0.001
Non-IPF ILD (251)	110 (43.8)	6.40	3.50–11.73	<0.001
IPF (191)	94 (49.2)	3.09	1.78–5.36	<0.001
CTD-ILD (136)	61 (44.9)	5.58	2.22–13.99	0.001
Other fibrotic ILD (115)	49 (42.6)	8.54	3.38–21.61	<0.001

All models adjusted for sex, race, smoking history and baseline body mass index (BMI), age, percent predicted forced vital capacity (FVC), percent predicted diffusion capacity of the lungs for carbon monoxide (DLCO), and CALIPER-derived measures total lung volume, pulmonary vascular-related structure volume and percent ground glass opacity, reticular opacity and honeycombing

Definitions of abbreviations: CTD = connective tissue disease; ILD = interstitial lung disease; IPF = idiopathic pulmonary fibrosis; qctPPF = quantitative CT measure of PPF