Table 3.
The multivariate Cox proportional hazard regression model of TNBC patients (WCH; N = 608).
| Variables | 5-year iDFS | 5-year overall survival | 5-year LRFS | |||
|---|---|---|---|---|---|---|
| HR (95% CI) | P-value | HR(95% CI) | P-value | HR(95% CI) | P-value | |
| Age (y) | ||||||
| ≤ 40 | Reference | Reference | Reference | |||
| 41–50 | 1.00 (0.50–1.99) | 0.999 | 0.75 (0.33–1.68) | 0.485 | 0.29 (0.05–1.58) | 0.152 |
| 51–60 | 0.72 (0.38–1.36) | 0.310 | 0.61 (0.29–1.28) | 0.188 | 0.56 (0.16–1.93) | 0.357 |
| ≥ 60 | 0.85 (0.44–1.64) | 0.635 | 0.74 (0.35–1.59) | 0.445 | 0.33 (0.07–1.49) | 0.150 |
| T stage | ||||||
| T1 | Reference | Reference | Reference | |||
| T2–4 | 1.45 (0.96–2.18) | 0.079 | 1.41 (0.83–2.39) | 0.203 | 1.49 (0.49–4.51) | 0.478 |
| N stage | ||||||
| N0 | Reference | Reference | Reference | |||
| N1–3 | 2.40 (1.67–3.46) | <0.001*** | 2.79 (1.72–4.53) | <0.001*** | 3.06 (1.14–8.17) | 0.026* |
| NACT | ||||||
| No | Reference | Reference | Reference | |||
| Yes | 0.68 (0.41–1.15) | 0.154 | 0.98 (0.54–1.80) | 0.959 | 1.13 (0.36–3.56) | 0.831 |
| Image score | 8.80 (4.85–15.96) | <0.001*** | 9.02 (4.24–19.17) | <0.001*** | 8.39 (1.96–35.97) | 0.004** |
*iDFS invasive disease-free survival, LRFS local recurrence–free survival, HR hazard ratio, NACT neoadjuvant chemotherapy. ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05.