Table 1.
The characteristics of patients with APALI.
| Characteristic | Training set (N = 1,480) a | Testing set (N = 495) a | External validation set (N = 224) a |
|---|---|---|---|
| Outcome | |||
| Non-APALI | 1,000 (68.57%) | 334 (67.47%) | 151 (67.41%) |
| APALI | 480 (32.43%) | 161 (32.53%) | 73 (32.59%) |
| Gender | |||
| Male | 834 (56.35%) | 275 (55.56%) | 154 (68.75%) |
| Female | 646 (43.65%) | 220 (44.44%) | 70 (31.25%) |
| Age (years) | 49 (37, 66) | 49 (38, 65) | 53 (41, 66) |
| Respiratory rate (cpm) | 21.20 (2.81) | 21.07 (2.70) | 20.71 (13.03) |
| Ca2+ (mmol/l) | 1.07 (1.00, 1.15) | 1.08 (1.01, 1.15) | 1.76 (1.26, 2.07) |
| Platelet (×10^9/l) | 206.0 (159.25, 256.0) | 194.0 (150.25, 255.0) | 199.0 (159.0, 269.5) |
| Neutrophil (×10^9/l) | 9.84 (6.95, 13.79) | 9.78 (6.40, 13.42) | 11.20 (7.90, 16.01) |
| Lymphocyte (×10^9/l) | 1.12 (0.79, 1.57) | 1.15 (0.78, 1.62) | 1.05 (0.75, 1.51) |
| Globulin (g/l) | 33.50 (29.7, 37.5) | 33.15 (28.98, 37.43) | 31.70 (28.83, 35.23) |
| Albumin (g/l) | 39.30 (34.6, 43.0) | 39.15 (35.0, 43.2) | 35.90 (31.0, 40.5) |
| Total cholesterol (mmol/l) | 4.01 (3.13, 5.46) | 3.95 (3.11, 5.35) | 3.84 (2.87, 5.22) |
| Pleural effusion | 488 (32.97%) | 177 (35.76%) | 67 (29.91%) |
| CTSI | |||
| A | 42 (2.84%) | 12 (2.42%) | 44 (19.64%) |
| B | 758 (51.22%) | 256 (51.72%) | 79 (35.27%) |
| C | 618 (41.75%) | 213 (43.03%) | 51 (22.77%) |
| D | 62 (4.19%) | 14 (2.83%) | 14 (6.25%) |
| E | 0 (0%) | 0 (0%) | 36 (16.07%) |
| Lactate (mmol/l) | 1.28 (0.84, 2.23) | 1.30 (0.84, 2.21) | 1.90 (1.08, 2.75) |
| BMI | 25.15 (3.09) | 25.08 (3.15) | 24.55 (3.52) |
| Temperature (°C) | 36.88 (0.54) | 36.84 (0.49) | 36.89 (1.09) |
| Pulse (bpm) | 92.95 (82.0, 100.0) | 92.95 (81.0, 99.0) | 92.95 (84.0, 101.0) |
| SBP (mmHg) | 133.51 (126.0, 140.0) | 133.51 (125.0, 139.0) | 133.51 (127.0, 141.0) |
| DBP (mmHg) | 79.19 (76.0, 87.0) | 79.19 (76.0, 88.0) | 79.19 (76.0, 86.0) |
| RDW | 13.69 (1.40) | 13.65 (1.29) | 13.63 (1.25) |
| Blood glucose (mmol/l) | 7.82 (6.15, 11.23) | 7.83 (6.01, 10.96) | 7.33 (5.85, 9.82) |
| NLR | 8.91 (5.15, 14.23) | 8.65 (5.11, 13.67) | 11.07 (6.86, 15.75) |
| C-reactive protein (mg/l) | 46.92 (12.29, 90.0) | 45.00 (11.18, 90.0) | 137.00 (35.0, 229.90) |
| TyG | 3.44 (3.07, 3.98) | 3.42 (3.01, 3.96) | 2.71 (2.27, 3.18) |
| PLR | 179.08 (126.49, 260.76) | 180.75 (123.17, 245.23) | 180.61 (110.37, 283.96) |
| NPR | 0.05 (0.03, 0.07) | 0.05 (0.03, 0.07) | 0.05 (0.04, 0.08) |
| NAR | 0.26 (0.18, 0.37) | 0.25 (0.17, 0.36) | 0.32 (0.22, 0.46) |
| Amylase (ln) b | 5.37 (4.39, 6.42) | 5.51 (4.44, 6.50) | 5.63 (4.63, 6.48) |
| Urinary Amylase (ln) b | 6.61 (5.51, 8.30) | 6.86 (5.82, 8.47) | 5.96 (5.25, 6.96) |
| Triglyceride (ln) b | 0.52 (0.08, 1.33) | 0.52 (−0.03, 1.28) | 0.46 (0.12, 1.05) |
| Procalcitonin (ng/ml) | −0.48 (−2.12, 0.66) | −0.63 (−2.21, 0.66) | 0.75 (0.23, 1.72) |
| SII (ln) b | 10.53 (9.98, 11.03) | 10.47 (9.95, 10.92) | 7.75 (7.13, 8.26) |
a
Mean (SD), Median (Q1, Q3); n (%).
b
ln, Natural logarithm.
CTSI, CT Severity Index; BMI, Body Mass Index; SBP, Systolic Blood Pressure; DBP, Diastolic Blood Pressure; RDW, Red Cell Distribution Width; NLR, Neutrophil-to-Lymphocyte Ratio; TyG, Triglyceride-Glucose Index; PLR, Platelet-to-Lymphocyte Ratio; NPR, Neutrophil-to-Platelet Ratio; NAR, Neutrophil-to-Albumin Ratio; SII, Systemic Inflammation Index.