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. 2025 Aug 26;30:804. doi: 10.1186/s40001-025-03100-6

Table 2.

ROC analysis of age, APACHE II, ISS, lactate, albumin, lactate clearance rate, LAR and combined indicators for predicting poor short-term prognosis in polytrauma (bootstrap-corrected)

Indicator AUC Standard Error P-value 95% CI Cut-off Value Sensitivity Specificity
Age (years) 0.636 0.61 0.03 0.517–0.755 57.5 0.500 0.765
APACHE II 0.931 0.020  < 0.01 0.884–0.977 22.5 0.857 0.894
ISS 0.812 0.040  < 0.01 0.735–0.889 20.5 1 0.565
Lactate at Admission (mmol/L) 0.663 0.060 0.04 0.548–0.777 4.745 0.571 0.718
Lactate at 24 h (mmol/L) 0.742 0.060  < 0.01 0.624–0.860 4.795 0.500 0.929
Lactate at 48 h (mmol/L) 0.886 0.040  < 0.01 0.811–0.960 2.08 0.857 0.847
Albumin at Admission (g/L) 0.596 0.070 0.15 0.466–0.726 32.25 0.571 0.659
Albumin at 24 h (g/L) 0.606 0.060 0.10 0.480–0.732 32.35 0.679 0.529
Albumin at 48 h (g/L) 0.704 0.060  < 0.01 0.593–0.814 28.75 0.536 0.800
LAR at Admission 0.667 0.060 0.04 0.550–0.784 0.183 0.464 0.859
LAR at 24 h 0.749 0.060  < 0.01 0.635–0.862 0.087 0.714 0.718
LAR at 48 h 0.901 0.030  < 0.01 0.838–0.965 0.074 0.857 0.859
lactate clearance 0.658 0.06  < 0.01 0.544–0.772 0.521 0.329 0.929
Composite Index 0.968 0.010  < 0.01 0.939–0.996 0.882 0.964 0.918

ROC receiver operating characteristic; APACHE II Acute Physiology and Chronic Health Evaluation II; ISS Injury Severity Score; LAR lactate albumin ratio