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. 2025 Aug 26;26:310. doi: 10.1186/s13063-025-08991-8

Table 2.

Most commonly reported characteristics of eligible studies (n = 81)*

Study Characteristic n (%)
Randomized Trial n (%) 80 (98.8)
Number Treatment Arms
 2 52 (64.2)
 3 20 (24.7)
Clinical Phase
 2 17 (21.0)
 3 61 (75.3)
Pharmacological intervention 81 (100.00)
Trial Type
 Non-inferiority 8 (9.9)
 Superiority 67 (82.7)
Commercial Status
 Industry sponsored 76 (93.8)

*81 protocols were eligible for review. Only selected results are shown in some categories, so sub-categories may not sum to 81. Full results are given in Supplement File 2, Table 2