Table 2.
Comparison of right heart catheterization results in each SSc patient group
| non-PH (n = 13) | exercise PH (N = 22) | PH (N = 15) | p-value | |
|---|---|---|---|---|
| RHC | ||||
| mPAWP (mmHg) | 7.0 ± 3.3 | 8.7 ± 2.9 | 10.8 ± 3.6 | 0.01 |
| mPAP (mmHg) | 15.0 ± 3.2 | 16.3 ± 3.8 | 31.9 ± 11.2 | < 0.0001 |
| CO (L/min) | 4.7 ± 1.7 | 4.5 ± 1.3 | 3.7 ± 1.1 | 0.08 |
| PVR (Wood units) | 1.8 ± 0.8 | 2.0 ± 1.7 | 6.4 ± 3.8 | < 0.0001 |
| SaO2 (%) | 96.6 ± 1.0 | 96.5 ± 1.4 | 90.2 ± 7.5 | 0.005 |
| SvO2 (%) | 75.6 ± 5.4 | 74.3 ± 4.2 | 67.8 ± 11.7 | 0.02 |
| exercise RHC | ||||
| mPAWP/CO (mmHg/L·min) | 1.0 ± 0.6 | 7.0 ± 7.2 | < 0.0001 | |
| mPAP/CO (mmHg/L·min) | 1.9 ± 0.7 | 14.9 ± 30.9 | < 0.0001 | |
| peak SaO2 (%) | 93.9 ± 2.7 | 94.1 ± 5.1 | 0.26 | |
| peak SvO2 (%) | 56.8 ± 12.1 | 49.5 ± 7.5 | 0.08 |
Values are reported as mean ± SD. Statistical differences were determined using the Kruskal–Wallis, Wilcoxon signed-rank, and Fisher’s exact tests. P < 0.05 was considered significant
SSc, systemic sclerosis; PH, pulmonary hypertension; exercise PH, exercise-induced pulmonary hypertension; WHO FC, World Health Organization functional class; RHC, right heart catheterization; mPAWP, mean pulmonary artery wedge pressure; mPAP, mean pulmonary artery pressure; CO, cardiac output; PVR, pulmonary vascular resistance; SaO2, arterial oxygen saturation; SvO2, mixed venous oxygen saturation