Table 3.

Maintenance treatment of vitamin D dependent rickets [4, 23]

Drug	VDDR1A	VDDR1B	VDDR2	VDDR3
Vitamin D	NI	Heterozygous 5000–10,000 IU/day Homozygous:600,000 every 3 months	LI	50,000/day
Calcifediol	NI	15–50 ug/day (preferred choice)	20–200 ug/day	50 to?
Alfacalcidol	10–100 ng/kg/day 0.5-3ug/day	0.5-3 ug/day (less effective)	10–400 ng/kg/day 5–60 ug/day	2 to?
Calcitriol	10–100 ng/kg/day 0.3-2 ug/day	0.3-2 ug/day (alternative choice)	10-400ng/kg/day 5-60ug/day	1 to?
Calcium salts (by oral route)	0.5–3 g/day	0.5–2 g/day	3–5 g/day 400–1400 mg/m2/day (IV route)	?

NI, Not indicated; LI, little indicated