Table 4.

Starting and maintenance doses of inorganic phosphate and active vitamin D analogs in hypophosphatemic rickets [30–35]

	Newborn or before the development of clinical or radiological signs of rickets	Evidence of clinical or radiological signs of rickets
Starting Doses	Alfacalcidol,25-40ng/kg/day (0.8-1ug/day), once/day. Inorganic phosphate salts, 20–40 mg/kg/day, 4 to 6 intakes/daily	Alfacalcidol, 40–80 ng/kg/day (1-1.5 ug/kg) once/day. Calcitriol, 20–40 ng/kg/day, 2–3 times/day Inorganic phosphate salts, 40–60 mg/kg/day, 4 to 6 intakes/daily
Maintenance doses	Alfacalcidol,25–40 ng/kg/day (1–2 ug/day), once/day; calcitriol,20–30 ng/kg/day. 2–3 times/day. inorganic phosphate salts, 20–60 mg/kg/day. 4 to 6 intakes/ day