Table 7.
Vitamin D supplementation in children with end stage renal disease (ESRD) [48]
| Age | 25(OH)D level (nmoI/L) | Daily dose | Monitoring |
|---|---|---|---|
| Intensive replacement therapy | |||
| < 1 year | < 12 | 600 IU/day |
Serum Ca and urinary Ca levels at 1–3 months. 25(OH)D after 3 months |
| > 1 year | 12–50 | 8000 IU/day |
Serum Ca and urinary Ca levels at 1–3 months. 25(OH)D after 3 months |
| 50–75 | 4000 IU/day |
Serum Ca and urinary Ca levels at 1–3 months. 25(OH)D after 3 months |
|
| Maintenance therapy | |||
| < 1 year | > 75 | 400 IU/day | 25(OH)D level at 6–12 months |
| > 1 year | > 75 |
1000/2000 IU/day (more in advanced CKD) |
25(OH)D level at 6–12 months |