Table 2.
Effect of treatment on organ weights of Male and Female rats calculated per 100 g of animal weight at different doses of MoS2 NF in sub-acute toxicity studies
| Organs | Female | Male | ||||
|---|---|---|---|---|---|---|
| Control group | MoS2NF | Control group | MoS2NF | |||
| 3 mg/kg | 10 mg/kg | 3 mg/kg | 10 mg/kg | |||
| Brain | 2.567 ± 0.127 | 2.933 ± 0.156 | 2.94 ± 0.107 | 2.770 ± 0.15 | 3.343 ± 0.143 | |
| Heart | 1.00 ± 0.064 | 1.103 ± 0.067 | 1.047 ± 0.081 | 0.767 ± 0.07 | 0.917 ± 0.105 | |
| Liver | 9.92 ± 0.18 | 11.81 ± 0.13*** | 12.61 ± 0.23*** | 6.82 ± 0.23 | 11.47 ± 0.26*** | |
| Lungs | 2.137 ± 0.27 | 3.99 ± 0.24** | 4.82 ± 0.326*** | 2.117 ± 0.102 | 3.13 ± 0.13** | |
| Ovary | 0.289 ± 0.107 | 0.250 ± 0.093 | 0.147 ± 0.029 | 2.96 ± 0.061 | 4.44 ± 0.121*** | |
| Kidney | 1.743 ± 0.142 | 1.110 ± 0.097* | 1.237 ± 0.137 | 1.087 ± 0.068 | 2.650 ± 0.144*** | |
Data are expressed as mean ± SEM, n = 5, *p < 0.05, **p < 0.01, ***p < 0.001 as compared with control. *indicates an increase in animals weight