Table 3.
Effect of MoS2 Nano flowers on complete blood count (CBC) in acute toxicity studies at different logarithmic doses
| Parameters | Unit | Normal control | MoS2 NF | |||||
|---|---|---|---|---|---|---|---|---|
| 1.75 mg/kg | 5.5 mg/kg | 17.5 mg/kg | 55 mg/ kg | 175 mg/kg | 550 mg/kg | |||
| Hemoglobin | g/dL | 10.3 ± 0.1 | 8.60 ± 0.1^^^ | 8.30 ± 0.1^^^ | 7.80 ± 0.1^^^ | 14.0 ± 0.1*** | 12.0 ± 0.1*** | 13.5 ± 0.1*** |
| RBCs | ×1012/L | 5.650 ± 0.33 | 4.90 ± 0.11 | 4.61 ± 0.190 | 4.07 ± 0.03^^ | 7.31 ± 0.31** | 6.75 ± 0.25* | 7.85 ± 0.25** |
| Neutrophils | % | 34.650 ± 2.15 | 26.50 ± 1.70 | 54.05 ± 1.55** | 42.20 ± 1.4 | 23.0 ± 3.0^ | 84.0 ± 1.0*** | 61.5 ± 4.50*** |
| Lymphocyte | % | 66.60 ± 1.60 | 63.10 ± 2.20 | 39.0 ± 2.0^^^ | 55.25 ± 0.95^ | 74.50 ± 1.5 | 13.0 ± 3.0^^^ | 40.0 ± 2.0^^^ |
| WBCs | ×109/L | 3.60 ± 0.10 | 3.30 ± 0.20 | 6.65 ± 0.150*** | 10.40 ± 0.20*** | 5.30 ± 0.1*** | 4.60 ± 0.20* | 3.35 ± 0.15 |
| Platelet count | ×109/L | 632.5 ± 17.5 | 470.0 ± 10.0 | 509 ± 11.0 | 565.0 ± 15.0 | 626.0 ± 7.50 | 737.0 ± 8.0 | 846.5 ± 5.50 |
Data are expressed as mean ± SEM, *P < 0.05, **P < 0.01, ***P < 0.001 as compared with control. *indicates increase levels while ^indicate decreased levels