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. 2025 Aug 26;20:456. doi: 10.1186/s13023-025-03987-8

Table 5.

Quantitative results of 5-point Likert scale of the impact inventory interview for parents

Question N Not at all % (n) Not very % (n) Neutral % (n) Somewhat % (n) Very % (n) Median3 Mean (SD)
PARENTS
Stress from first symptoms to diagnosis 78 1.3% (1) 7.7% (6) 2.6% (2) 14.1% (11) 74.4% (58) 4 3.5 (1.0)
Well-informed after diagnosis 77 20.8% (16) 32.5% (25) 6.5% (5) 16.9% (13) 23.4% (18) 1 1.9 (1.5)
Satisfied with diagnosis communication 78 12.8% (10) 11.5% (9) 19.5% (15) 30.8% (24) 25.6% (20) 3 2.5 (1.3)
Stress after diagnosis 78 0.0% (0) 1.3% (1) 3.8% (3) 11.5% (9) 83.3% (65) 4 3.8 (0.6)
Hope for finding a cure 78 10.3% (8) 7.7% (6) 7.7% (6) 28.2% (22) 46.1% (36) 3 2.9 (1.3)
Worried about acute deterioration 76 2.6% (2) 4.0% (3) 7.9% (6) 29.0% (22) 56.6% (43) 4 3.3 (1.0)
Frequency of worry about deterioration 78 1.3% (1) 6.4% (5) 15.4% (12) 32.1% (25) 44.9% (35) 3 3.1 (1.0)
Impact preventive measures on family life 77 1.3% (1) 5.2%(4) 9.1% (7) 36.4% (28) 48.1% (37) 3 3.3 (0.9)
Burden of caregiving1 78 19.2% (15) 6.4%(5) 23.1% (18) 34.6% (27) 16.7% (13) 3 2.2 (1.4)
Career satisfaction 77 9.1% (7) 7.9% (6) 24.7% (19) 27.3% (21) 31.2%(24) 3 2.6 (1.3)
Concerned about finances 78 11.5% (9) 29.5% (23) 12.8% (10) 33.3% (26) 12.8% (10) 2 2.1 (1.3)
Social acceptance of VWM 78 2.6% (2) 12.8% (10) 29.5% (23) 38.5% (30) 16.7% (13) 3 2.5 (1.0)
Current knowledge of VWM 77 0.0% (0) 5.2% (4) 3.9% (3) 40.3% (31) 50.7% (39) 4 3.4 (0.8)
Know more than healthcare professionals2 78 6.4% (5) 10.3% (8) 19.2% (15) 30.8% (24) 33.3% (26) 3 2.7 (1.2)
PARTNERS
Stress from first symptoms to diagnosis 6 0.0% (0) 16.7% (1) 16.7% (1) 67.7% (4) 0.00% (0) 3 2.5 (0.8)
Well-informed after diagnosis 6 0.0% (0) 16.7% (1) 0.0% (0) 67.7% (4) 16.7% (1) 3 2.8 (1.0)
Satisfied with diagnosis communication 6 0.0% (0) 0.0% (0) 0.0% (0) 67.7% (4) 33.3% (2) 3 3.3 (0.5)
Stress after diagnosis 6 0.0% (0) 16.7% (1) 0.0% (1) 33.3% (2) 50.0% (3) 3.5 3.2 (1.2)
Hope for finding a cure 6 33.3 (2) 33.3 (2) 0.0% (0) 16.7 (1) 16.7 (1) 1 1.5 (1.6)
Worried about acute deterioration 6 0.0% (0) 16.7% (1) 0.0% (0) 50.0% (3) 33.3% (2) 3 3.0 (1.1)
Frequency of worry about deterioration 6 0.0% (0) 16.7% (1) 0.0% (0) 67.7% (4) 16.7% (1) 3 2.8 (1.0)
Impact preventive measures on family life 6 0.0% (0) 0.0% (0) 16.7% (1) 50.0% (3) 33.3% (2) 3 3.2 (0.8)
Burden of caregiving1 6 0.0% (0) 0.0% (0) 33.3% (2) 16.7% (1) 50.0% (3) 3.5 3.2 (1.0)
Career satisfaction 6 0.0% (0) 16.7% (1) 16.7% (1) 16.7% (1) 50.0% (3) 3.5 3.0 (1.3)
Concerned about finances 6 33.3% (2) 0.0% (0) 33.3% (2) 33.3% (2) 0.0% (0) 2 1.7 (1.4)
Social acceptance of VWM 6 0.0% (0) 50.0 (3) 16.7% (1) 0.00% (0) 33.3% (2) 1.5 2.2 (1.5)
Current knowledge of VWM 6 0.0% (0) 16.7% (1) 0.0% (0) 67.7% (4) 16.7% (2) 3 2.8 (1.0)
Know more than healthcare professionals2 6 0.0% (0) 0.0% (0) 33.3% (2) 33.3% (2) 33.3% (2) 3 3.0 (0.8)
Question n Not at all % (n) Rarely % (n) Neutral % (n) Often % (n) Almost always % (n) Median3 Mean (SD)
SIBLINGS
Thinks about sibling having VWM 13 0.0% (0) 0.0% (0) 23.1% (3) 69.2% (9) 7.7% (1) 3 2.9 (0.6)
Talks about it with friends 13 15.4% (2) 7.7% (1) 61.5% (8) 15.4% (2) 0.0% (0) 2 1.8 (0.9)
Talks about it with parents 13 15.4% (2) 15.4% (2) 38.5% (5) 15.4% (2) 15.4% (2) 2 2.0 (1.3)
Talks about it with someone else 13 23.1% (3) 15.4% (2) 46.2 (6) 15.4% (2) 0.0% (0) 2 1.5 (1.0)
Helps taking care of sibling 13 0.0% (0) 0.0% (0) 38.5% (5) 46.2% (6) 15.4% (2) 3 2.8 (0.7)
Misses school or work 13 53.9% (7) 38.5% (5) 7.7% (1) 0.0% (0) 0.0% (0) 0 0.5 (0.7)

1Scale: “absolutely not burdensome”, “not burdensome”, “neutral”, “burdensome”, “very burdensome”. 2Scale: “know absolutely less”, “know less”, “neutral”, “know more”, “know absolutely more”. 3Range of the median is for all questions 0–4. Notable items are marked in bold

N, total number; n, number