Table 3.
Chi-square analysis on risk factors of neonates acquiring early-onset sepsis
| Risk factors | Sepsis group (N = 1449) |
Non-sepsis group (N = 7245) |
p value |
|---|---|---|---|
| Maternal factors | |||
| Maternal fever | 10 (0.69) | 17 (0.23) | 0.004 |
| Chorioamnionitis | 17 (1.17) | 5 (0.07) | < 0.001 |
| Maternal genitourinary tract infections | 47 (3.24) | 94 (1.30) | < 0.001 |
| Maternal group B streptococcus (GBS) colonization | 54 (3.73) | 241 (3.33) | 0.442 |
| Maternal pneumonia | 20 (1.38) | 6 (0.08) | < 0.001 |
| Premature rupture of membranes (PROM) | 98 (6.76) | 312 (4.31) | < 0.001 |
| Delivery by Cesarean section | 681 (47.00) | 2546 (35.14) | < 0.001 |
| Maternal systemic lupus erythematosus (SLE) | 9 (0.62) | 28 (0.39) | 0.2104 |
| Maternal diabetes mellitus | 95 (6.56) | 264 (3.64) | < 0.001 |
| Maternal antibiotics usage | 500 (34.51) | 1841 (25.40) | < 0.001 |
| Steroid (betamethasone or dexamethasone) usage | 23 (1.59) | 60 (0.83) | 0.007 |
| Neonatal factors | |||
| Gestational age (weeks)* | 38 ± 1 | 39 ± 1 | < 0.001 |
| Birth body weight (per 100 g)* | 29.87 ± 5.85 | 31.21 ± 3.79 | < 0.001 |
| Birth injury | 3 (0.21) | 20 (0.28) | 0.641 |
| Meconium aspiration syndrome (MAS) | 5 (0.35) | 23 (0.32) | 0.866 |
Data are presented as number (percentage among total positive cases for each risk factor), unless otherwise specified
*Continuous variables are shown as mean ± standard deviation