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. 2025 Aug 26;24:267. doi: 10.1186/s12944-025-02682-8

Table 6.

Subgroup analysis of TG/HDL-C in relation to positive pus or blood cultures

Confounding factors TG/HDL-C
OR(95%CI)P
Q1 Q2
OR(95%CI)P
Q3
OR(95%CI)P
Q4
OR(95%CI)P
P for interaction
Gender 0.058
Male 1.03 (1.00, 1.05) 0.026 1.0 0.87 (0.62, 1.23) 0.424 1.29 (0.91, 1.82) 0.147 1.88 (1.33, 2.66) < 0.001
Female 1.08 (1.03, 1.14) 0.002 1.0 1.06 (0.68, 1.65) 0.799 1.09 (0.69, 1.70) 0.718 2.08 (1.26, 3.42) 0.004
Age (years) 0.127
<60 1.06 (1.02, 1.10) 0.001 1.0 0.73 (0.49, 1.08) 0.116 1.04 (0.70, 1.54) 0.843 2.37 (1.55, 3.63) < 0.001
≥60 1.02 (1.00, 1.05) 0.089 1.0 1.17 (0.81, 1.71) 0.401 1.41 (0.96, 2.07) 0.076 1.60 (1.09, 2.35) 0.016
Diabetes mellitus 0.299
No 1.05 (1.01, 1.09) 0.007 1.0 0.96 (0.69, 1.34) 0.805 1.50 (1.06, 2.12) 0.022 2.17 (1.49, 3.16) < 0.001
Yes 1.03 (1.00, 1.05) 0.065 1.0 0.70 (0.42, 1.15) 0.156 0.70 (0.43, 1.15) 0.158 1.23 (0.75, 2.01) 0.419
Fatty liver 0.160
No 1.03 (1.01, 1.06) 0.006 1.0 0.92 (0.68, 1.25) 0.604 1.25 (0.93, 1.70) 0.142 1.94 (1.41, 2.65) < 0.001
Yes 1.08 (1.01, 1.16) 0.018 1.0 0.98 (0.51, 1.90) 0.957 1.08 (0.56, 2.07) 0.823 1.94 (0.99, 3.80) 0.051
BMI (kg/m2) 0.215
<25 1.07 (1.02, 1.12) 0.002 1.0 0.90 (0.62, 1.30) 0.566 1.07 (0.73, 1.58) 0.716 2.42 (1.56, 3.75) < 0.001
≥25 1.03 (0.98, 1.08) 0.221 1.0 0.79 (0.44, 1.41) 0.423 1.04 (0.55, 1.95) 0.909 1.19 (0.66, 2.15) 0.560
WBC (109/L) 0.006
<10 1.11 (1.05, 1.18) 0.001 1.0 1.01 (0.64, 1.58) 0.974 1.62 (1.01, 2.58) 0.044 4.23 (2.41, 7.40) < 0.001
≥10 1.02 (1.00, 1.05) 0.073 1.0 0.96 (0.67, 1.35) 0.799 1.07 (0.76, 1.50) 0.716 1.41 (1.01, 1.98) 0.047
CRP (mg/L) 0.168
<8 0.64 (0.30, 1.39) 0.259 1.0 0.37 (0.03, 4.71) 0.447 0.27 (0.04, 1.95) 0.196 0.00 (0.00, Inf) 0.995
≥8 1.06 (1.03, 1.09) < 0.001 1.0 0.76 (0.56, 1.03) 0.079 1.19 (0.87, 1.62) 0.281 1.86 (1.34, 2.59) < 0.001
PCT (ng/mL)
<0.05 0.52 (0.16, 1.71) 0.281 1.0 0.33 (0.02, 6.65) 0.472 0.33 (0.03, 4.19) 0.395 0.00 (0.00, Inf) 0.997 0.200
≥0.05 1.05 (1.02, 1.08) < 0.001 1.0 0.85 (0.64, 1.13) 0.269 1.20 (0.90, 1.61) 0.215 1.87 (1.38, 2.53) < 0.001

OR odds ratio, CI confidence interval, Q quartile, TG triglycerides, HDL-C high-density lipoprotein cholesterol, BMI body mass index, WBC white blood cells , CRPC-reactive protein, PCT procalcitonin