Figure 2. The impact of column parameters and n-Dodecyl-β-D-maltoside (DDM) on timsTOF SCP sensitivity.

The default parameters were configured as follows: 30min gradient time, 166ms ramp time and a 20 m/z isolation window. (A) Percentage of identified precursors and (B) percentage of identified proteins with different loading amount of HeLa cell digest (n = 3). 100% equivalents to 33,434 precursors in Fig 2A and 3,868 proteins in Fig 2B.