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. 2025 Aug 26;25:820. doi: 10.1186/s12888-025-07278-1

Table 4.

Mediation analysis of CRP in the association between dietary niacin intake and suicidal ideation

Independent variable Mediator Total effect Indirect effect Direct effect Proportion mediated, %
Coefficient (95% CI) P value Coefficient (95% CI) P value Coefficient (95% CI) P value
Niacin intake CRP −0.0257 (−0.0481, −0.011) < 0.001 −0.0009 (−0.0015, −0.0003) 0.006 −0.0248 (−0.0471, −0.0102) < 0.001 3.6

Gender, age, race, drinking, BMI, smoking, physical activities, CHD, hyperlipidemia, stroke, PIR, education level, marital status, albumin, creatinine, depression disorder, and cancer were adjusted