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. 2025 Aug 26;25:552. doi: 10.1186/s12866-025-04291-y

Table 4.

Functional insight of yeast species in relation to biocontrol potential

Species Functions Reference
H. guilliermondii Colonizes grape wound sites and inhibits Aspergillus spp. in Thompson Seedless cultivar. Exhibits antagonistic activity against Botrytis cinerea, A. carbonarius, and P. expansum. [7, 53]
H. uvarum Acts as a biocontrol agent against B. cinerea, P. expansum, and A. carbonarius through lytic enzyme production that hydrolyzes fungal cell walls. Also effective against A. tubingensis and P. commune. [7, 54, 55]
P. kudriavzevii Reduces gray mold in grapes by producing VOCs. Exhibits antagonistic activity against A. niger and A. alternata. [56, 57]
P. kluyveri Functions as a bioprotective agent in wine fermentation, reducing the need for sulfites. Shows antagonistic activity against B. cinerea and M. laxa, and inhibits hyphal growth of B. cinerea and P. expansum. [7, 10]
P. manshurica Functions as a biocontrol agent for postharvest grape diseases. [58]
P. terricola Inhibits Penicillium glabrum, a spoilage fungus in grapes and wine. [59]
P. sporocuriosa Identified as part of grape yeast diversity. Functional application not yet well studied [38]
P. fermentans Potential to reduce hyphal growth of grape pathogens like B. cinerea and P. expansum. [7]
M. caribbica Produces VOCs with antifungal effects against A. fumigatus, F. poae, P. chrysogenum, Mucor spp., and B. cinerea. [9]
N. nivariensis Not yet reported in grape environments.
Z. hellenicus No evidence of biocontrol activity reported.
Z. bailii No evidence of biocontrol activity reported.
L. thermotolerans Exhibits antagonistic activity against Mucor, Aspergillus, and Botrytis spp. Controls growth of A. carbonarius and A. niger and reduces ochratoxin A accumulation. [21, 60]
S. stellimalicola No evidence of biocontrol activity reported.
C. parapsilosis No evidence of biocontrol activity reported.
W. sorbophila No evidence of biocontrol activity reported.
W. anomalus Acts as a biocontrol agent during winemaking, targeting Dekkera/Brettanomyces via toxin secretion. Antagonistic activity against B. cinerea. [51, 57]
S. diversa Exhibits antagonistic activity against a broad range of fungal pathogens, significantly reducing B. cinerea growth. [61]