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. 2025 Aug 26;30:807. doi: 10.1186/s40001-025-03063-8

Table 2.

Linear regression for the associations between CSVD burden score and motor parameters in CSVD patients

Dependent variables CSVD burden score
Univariable regression Multivariable regression—model 1 Multivariable regression—model 2
β (95% CI) P β (95% CI) P β (95% CI) P
SPPB score  − 0.502 (− 0.811–−0.194) 0.002  − 0.400 (− 0.712–−0.088) 0.013  − 0.454 (− 0.827–−0.080) 0.020
Speed  − 0.052 (− 0.082–−0.021) 0.001  − 0.041 (− 0.071–−0.011) 0.009  − 0.029 (− 0.068–0.011) 0.161
Stride length  − 0.048 (− 0.074–−0.022)  < 0.001  − 0.038 (− 0.064–−0.012) 0.005  − 0.029 (− 0.064–0.005) 0.098
Stride time 0.182 (− 0.133–0.498) 0.259 0.147 (− 0.178–0.472) 0.378 0.004 (− 0.024–0.031) 0.793
Support phase 0.009 (− 0.487–0.505) 0.972 0.046 (− 0.469–0.561) 0.862  − 0.081 (− 0.748–0.585) 0.812
Hip ROM  − 10.245 (− 18.008–−2.482) 0.011  − 9.213 (− 17.205–−1.222) 0.026  − 4.310 (− 11.792–3.173) 0.263
Knee ROM  − 1.705 (− 2.701–−0.709) 0.001  − 1.360 (− 2.359–−0.360) 0.009  − 1.016 (− 2.302–0.270) 0.126
Ankle ROM  − 3.050 (− 6.483–0.384) 0.084  − 3.062 (− 6.611–0.488) 0.093  − 3.729 (− 8.950–1.493) 0.166

SPPB Short Physical Performance Battery; ROM range of motion; CI confidence interval

Multivariable regression—model 1 adjusted for age

Multivariable regression—model 2 adjusted for age and MoCA score