Table 1.
Case demographics and clinical archived information
| No. | Group | Species | Age | Gestational age | Tissue collection time | Euthanasia/cause of death | Case pathologic finding |
|---|---|---|---|---|---|---|---|
| 1 | C | R | 4 y 10 mo | Early third trimester | 4 h postmortem | Euthanized due to emaciation, chronic diarrhea, weight loss, hindlimb atrophy | Pathology: normal gravid uterus |
| 2 | C | R | 14 y | Full term | Unknown | Not applicable | Pathology: normal placenta |
| 3 | C | H | 32 y | 39 wk 2 d | At delivery | Not applicable | Spontaneous labor Pathology: normal placenta |
| 4 | RP | R | 11 y | Full term | 32 h postmortem | Euthanized secondary to concern for poor prognosis after retained placenta management Clinical examination: lethargic animal concerning for hypovolemic shock and septicemia |
Umbilical cord protruding from vulva and attached to infant Ultrasound: complete retained placenta D&C attempted but complicated by full uterine prolapse Bacteriology: Acinetobacter lwoffii, normal uterine microflora Pathology: moderate multifocal erosive suppurative endometritis, normal placenta |
| 5 | RP | R | 19 y 2 mo | Full term | 4 h postmortem | Euthanized due to neurologic deficits Clinical examination: lethargy and dehydration secondary to endometritis |
Uterus enlarged and firm Ultrasound: mixed echogenic mass within uterus suggestive of retained placental fragments D&C performed with retrieval of placental tissue Bacteriology: Staphylococcus aureus isolated from heart, blood, and uterine swab Pathology: moderate multifocal suppurative endometritis |
| 6 | RP | R | 4 y 11 mo | Full term | 8 h postmortem | Clinical examination: animal found deceased postdelivery secondary to hemorrhage | On necropsy partial retained placenta attached at fundus Bacteriology: uterine swab with Staphylococcus warneri and Aerococcus viridans, but tissue section without infectious process Pathology: marked hemorrhage dissecting into myometrium |
| 7 | RP | H | 35 y | 37 wk 2 d | At delivery | Not applicable | Pathology: umbilical venous congestion, increased perivillous fibrin, focal intraplacental hematoma |
| 8 | RP | H | 39 y | 39 wk 2 d | At delivery | Not applicable | Pathology: mild distal villous hypoplasia |
| 9 | RP | H | 32 y | 35 wk 0 d | At delivery | Not applicable | Pathology: increased perivillous fibrin |
| 10 | RP | H | 30 y | 39 wk 1 d | At delivery | Not applicable | Pathology: increased syncytial knots, mild distal villous hypoplasia, amnion hyperplasia |
| 11 | RP | H | 35 y | 37 wk 3 d | At delivery | Not applicable | Pathology: disrupted maternal surface 30%, accessory lobe |
| 12 | RP | H | 37 y | 39 wk 5 d | At delivery | Not applicable | Pathology: normal placenta |
| 13 | RP | H | 20 y | 39 wk 3 d | At delivery | Not applicable | Pathology: increased perivillous fibrin and calcifications |
| 14 | RP | H | 32 y | 33 wk 4 d | At delivery | Not applicable | Pathology: disrupted maternal surface |
| 15 | RP | H | 32 y | 31 wk 5 d | At delivery | Not applicable | Pathology: funisitis, amnion hyperplasia |
| 16 | RP | H | 26 y | 32 wk 3 d | At delivery | Not applicable | Pathology: focal maternal fibrinoid decidual vasculopathy with atherosclerosis and watershed infarction, peripheral increased syncytial knots, hemorrhage |
| 17 | RP | H | 31 y | 38 wk 2 d | At delivery | Not applicable | Pathology: normal placenta |
C, control; D&C, dilation and curettage; H, human; R, rhesus; RP, retained placenta.