Table 3. Core body temperature (CBT) metrics in participants with systemic inflammation (SI) and controls^a.

Diagnosis		Nadir CBT (°C)	Peak CBT (°C)	Mean CBT (SD) (°C)
Patients with SI
1	Adult-onset Still disease	36.4	38.5	37.3 (0.708)
2	VEXASb syndrome	36.4	37.0	36.6 (0.151)
3	Peripheral SpAc	36.7	37.2	36.9 (0.102)
4	Undifferentiated seronegative polyarthritis	36.3	36.8	36.6 (0.117)
5	Giant cell arteritis	36.3	36.8	36.5 (0.114)
6	Multiple sclerosis	36.8	37.1	36.9 (0.062)
	SI group average	36.5	37.2	36.8 (0.209)
Controls
7	No inflammatory disease	36.7	37.5	37.0 (0.228)
8	No inflammatory disease	36.4	37.2	36.6 (0.148)
9	RAd in remission	36.3	36.9	36.5 (0.127)
10	No inflammatory disease	36.4	36.8	36.6 (0.094)
11	No inflammatory disease	36.8	37.3	37.0 (0.094)
12	No inflammatory disease	36.6	37.1	36.8 (0.133)
13	SpA in remission	36.3	36.8	36.6 (0.163)
	Control group average	36.5	37.1	36.7 (0.141)

^aFor each participant, minimum (nadir), maximum (peak), and mean (SD) of CBT were calculated based on the temperature measurements collected between 10 PM and 7 AM the following day.

^bVEXAS: vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic.

^cSpA: spondyloarthritis.

^dRA: rheumatoid arthritis.