Table 4.
Diagnostic Accuracy Analysis for Identification High-Grade Histopathologic Patterns of Adenocarcinoma Across Small Biopsy and Surgical Resection Specimens (n=66):
| Surgical Resection Specimen | ||||
| Poorly Differentiated | Non-Poorly Differentiated | |||
| Biopsy Specimen | High Grade Pattern Identified | 17 (63%) | 11 (47%) | 28 (43%) |
| High Grade Pattern Not Identified | 10 (27%) | 28 (73%) | 38 (57%) | |
| 27 (41%) | 39 (59%) | 66 (100%) | ||
| Accuracy: 68% Sensitivity: 63% Specificity: 72% Positive predictive value: 61% Negative predictive value: 74% | ||||
| Surgical Resection Specimen | ||||
| Pure IMA or mixed nonmucinous-IMA | Nonmucinous Adenocarcinoma | |||
| Biopsy Specimen | Compatible with IMA | 8 (89%) | 2 (4%) | 10 (15%) |
| Incompatible with IMA | 1 (11%) | 55 (96%) | 56 (85%) | |
| 9 (14%) | 57 (86%) | 66 (100%) | ||
| Accuracy: 95% Sensitivity: 89% Specificity: 96% Positive predictive value: 80% Negative predictive value: 98% | ||||
CI, confidence interval; IMA, invasive mucinous adenocarcinoma.