Table 1.
Associations of factors with favorable pathology risk cores patterns in 757 patients treated with robotic surgery
| Favorable pathology risk score pattern in the surgical specimen | p | ||||
|---|---|---|---|---|---|
| Zero | One | Two | Three | ||
| Cases, n (%) | 15 (15.2) | 371 (49.0) | 234 (30.9) | 37 (4.9) | |
| Physical features | |||||
| Age (years) | 63 (58–68) | 64 (58–69) | 65 (61–71) | 66 (60.5–70.5) | 0.005 |
| BMI [kg/m2] | 25.6 (23.7–28.0) | 25.8 (24.0–27.8) | 26.0 (23.9–28.1) | 26.1 (22.8–28.5) | 0.729 |
| ASA score 1 | 13 (4.3) | 36 (9.7) | 17 (7.3) | 5 (13.5) | 0.266 |
| ASA score 2 | 96 (83.5) | 304 (81.9) | 189 (80.8) | 27 (73.0) | |
| ASA score 3 | 6 (5.2) | 31 (8.4) | 28 (12.0) | 5 (13.5) | |
| PV [ml] | 42 (32–53) | 40 (30–50) | 36.7 (28.7–47.2) | 34 (30–47) | 0.054 |
| Clinical cancer features | |||||
| PSA [ng/ml] | 6.1 (4.6–7.9) | 6.2 (4.7–8.1) | 6.4 (5.0–8.6) | 8.1 (5.6–10.1) | 0.007 |
| BPC (%) | 21.4 (14.2–35.7) | 28.5 (16.6–42.8) | 30 (20–50) | 30 (21.8–51.6) | <0.0001 |
| ISUP 1 | 96 (83.5) | 156 (42.0) | 62 (26.5) | 7 (18.9) | <0.0001 |
| ISUP 2/3 | 19 (16.5) | 209 (56.3) | 160 (68.4) | 30 (81.1) | |
| ISUP 4/5 | 0 (0.0) | 6 (1.6) | 12 (5.1) | 0 (0.0) | |
| cT1 | 90 (78.3) | 232 (62.5) | 138 (59.0) | 16 (43.2) | <0.0001 |
| cT2/3 | 25 (21.7) | 139 (37.5) | 96 (41.0) | 21 (56.8) | |
| EAU risk class | |||||
| Low-risk | 92 (80) | 122 (32.9) | 51 (21.8) | 4 (10.8) | <0.0001 |
| Intermediate-risk | 19 (16.5) | 219 (59.0) | 149 (63.7) | 25 (67.6) | |
| High-risk | 4 (3.5) | 30 (8.1) | 34 (14.5) | 8 (21.6) | |
| Nomogram for PLNI | |||||
| Briganti 2012 (%) | 2 (1–3) | 2 (1–4) | 4 (2–8) | 4 (2.5–8.5) | <0.0001 |
| PLND | 32 (27.8) | 199 (53.6) | 157 (67.1) | 27 (73.0) | <0.0001 |
| Pathology features | |||||
| ISUP 1 | 115 (100) | 1 (0.3) | <0.0001 | ||
| ISUP 2 | 370 (99.7) | 20 (8.5) | |||
| ISUP 3 | 214 (91.5) | 37 (100) | |||
| pT2 | 115 (100) | 370 (99.7) | 214 (91.5) | <0.0001 | |
| pT3a | 1 (0.3) | 20 (8.5) | 37 (100) | ||
| R1 | 12 (10.4) | 74 (19.9) | 42 (17.9) | 20 (54.1) | <0.0001 |
Continuous variables are reported as medians (interquartile ranges) while categorical factors as frequencies (percentages); and methods; for further details see sections relative to material
ASA – American Society of Anesthesiologists; BMI – body mass index; EAU – European Association of Urology