Table 1.
Characteristics of survivors of childhood cancer participating and non-participants in the St Jude Lifetime Cohort.
|
Participants n = 2433 |
Non-participants n= 404 |
p |
|||
|---|---|---|---|---|---|
| Age in years, median (range)a | 27.9 | (18.0 – 64.8) | 32.3 | (18.0 – 63.3) | <0.01 |
| Age at diagnosis in years, median (range)a | 9.2 | (0.1 – 24.5) | 8.8 | (0.1 – 23.5) | <0.01 |
| Sex, n (%) | |||||
| Male | 1260 | (51.8) | 191 | (47.3) | 0.09 |
| Female | 1173 | (48.2) | 213 | (52.7) | |
| Race, n (%)b | |||||
| White | 1,999 | (82.2) | 345 | (85.4) | <0.01 |
| Black | 368 | (15.1) | 57 | (13.5) | |
| Other | 65 | (2.7) | 1 | (0.25) | |
| Unknown | 1 | (0.04) | 1 | (0.25) | |
| Primary neoplasm, n (%) | |||||
| Acute lymphoblastic leukemia | 658 | (27.0) | 102 | (25.3) | 0.51 |
| Acute myeloid leukemia | 89 | (3.7) | 22 | (5.5) | |
| Other leukemia | 17 | (0.7) | 4 | (0.9) | |
| Hodgkin lymphoma | 340 | (14.0) | 51 | (12.6) | |
| Non-Hodgkin lymphoma | 152 | (6.3) | 30 | (7.4) | |
| Central nervous system | 366 | (15.0) | 62 | (15.3) | |
| Wilms tumor | 139 | (5.7) | 27 | (6.7) | |
| Neuroblastoma | 103 | (4.2) | 9 | (2.2) | |
| Bone tumor | 188 | (7.7) | 27 | (6.7) | |
| Retinoblastoma | 74 | (3.0) | 14 | (3.5) | |
| Soft tissue sarcoma | 152 | (6.3) | 29 | (7.2) | |
| Other | 155 | (6.4) | 27 | (6.7) | |
| Alkylating agent, n (%) | |||||
| Yes | 1,452 | (59.7) | 233 | (57.7) | 0.38 |
| No | 981 | (40.3) | 171 | (42.3) | |
| Heavy metal, n (%) | |||||
| Yes | 368 | (15.1) | 60 | (14.8) | 0.88 |
| No | 2,065 | (84.9) | 344 | (85.2) | |
| Anthracycline, n (%) | |||||
| Yes | 1,400 | (57.5) | 226 | (55.9) | 0.55 |
| No | 1,033 | (42.5) | 178 | (44.1) | |
| Corticosteroids, n (%) | |||||
| Yes | 1,055 | (43.4) | 158 | (39.1) | 0.11 |
| No | 1,378 | (56.6) | 246 | (60.9) | |
| Bleomycin, n (%) | |||||
| Yes | 180 | (7.4) | 24 | (5.9) | 0.29 |
| No | 2,253 | (92.6) | 380 | (94.1) | |
| Chest radiation, n (%) | |||||
| Yes | 695 | (28.5) | 110 | (27.2) | 0.58 |
| No | 1,738 | (71.5) | 294 | (72.8) | |
Chi-square or t-test unless otherwise noted
Mann-Whitney U test was used
SD = standard deviation;