Table 2.
Characteristics of survivors with low and normal cardiopulmonary fitness levels based on if they are above or below the median of percent predicted VO2
|
Normal cardiopulmonary fitness |
Low cardiopulmonary fitness |
p |
|||
|---|---|---|---|---|---|
| n = 1,099 | n = 1,221 | ||||
|
|
|
|
|||
| Age in years, mean median (range)a | 27.9 | (18.0 – 64.5) | 27.7 | (18.0 – 64.8) | 0.48 |
| Age at diagnosis in years, median (range)a | 9.6 | (0.1 – 24.4) | 9.1 | (0.1 – 23.5) | 0.15 |
| Sex, n (%) | |||||
| Male | 565 | (51.4) | 633 | (55.4) | 0.59 |
| Female | 534 | (48.9) | 588 | (44.6) | |
| Race, n (%)b | |||||
| White | 948 | (86.3) | 961 | (78.7) | <0.01 |
| Black | 112 | (10.2) | 233 | (2.2) | |
| Other | 39 | (3.5) | 27 | (19.1) | |
| Peak METS achieved on CPET, mean (SD) | 9.1 | (2.3) | 6.1 | (1.7) | <0.01 |
| Met physical activity guidelinesc, n (%) | |||||
| Yes | 707 | (64.3) | 478 | (39.1) | <0.01 |
| No | 392 | (35.7) | 743 | (60.9) | |
| Smoker, n (%) | |||||
| Past | 149 | (13.6) | 146 | (11.9) | 0.38 |
| Current | 189 | (17.2) | 199 | (16.3) | |
| Never | 761 | (69.2) | 876 | (71.8) | |
| Cardiovascular disease at baseline, n (%) | |||||
| Yes | 112 | (10.2) | 248 | (20.3) | <0.01 |
| No | 987 | (89.8) | 973 | (79.7) | |
| Obesity at baseline, n (%) | |||||
| Yes | 722 | (65.7) | 848 | (69.5) | 0.05 |
| No | 377 | (34.3) | 373 | (30.5) | |
| Hypertension at baseline, n (%) | |||||
| Yes | 211 | (19.2) | 344 | (28.2) | <0.01 |
| No | 888 | (80.8) | 877 | (71.8) | |
| Abnormal glucose metabolism at baseline, n (%) | |||||
| Yes | 56 | (5.1) | 137 | (11.2) | <0.01 |
| No | 1,043 | (94.9) | 1,084 | (88.8) | |
Chi-square or t-test unless otherwise noted
a
Mann-Whitney U test was used
b
Fisher’s exact test used
c
Physical activity guidelines based off the Center for Disease Control’s 2008 physical activity recommendations of 450 metabolic equivalent hours per week56
SD = standard deviation; METS = metabolic equivalent, CPET = cardiopulmonary exercise test, SD= standard deviation