Table 4.
Uni- and Multivariate Predictors of Clinical Events (Death and/or HF Hospitalization) by Cox and Stepwise Regression Analysis
| Variable | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P Value | HR (95% CI) | P Value | |
| Male gender | 1.33 (0.82–2.16) | 0.25 | ||
| NHYA class (III-IV) | 2.51(1.31–4.81) | 0.01 | 0.21(0.04–0.37) | 0.015 |
| BMI>24kg/m2 | 0.32(0.19–0.55) | <0.001 | −0.30 (−0.45- −0.15) | <0.001 |
| Beta-blockers (%) | 1.02(0.63–1.63) | 0.95 | 0.20(0.04–0.37) | 0.016 |
| LAVI (mL/m2) | 1.03(0.99–1.06) | 0.16 | ||
| LVEDVI (mL) | 1.02(1.01–1.03) | <0.001 | ||
| LVESV (mL) | 1.03(1.01–1.04) | <0.001 | ||
| LVEF (%) | 0.92(0.83–1.01) | 0.09 | ||
| Relative change in LV GLS | 1.13(1.03–1.24) | 0.010 | ||
| LASr (%) | 0.86 (0.81–0.92) | <0.001 | ||
| LAScd (%) | 1.24(1.12–1.37) | <0.001 | 0.07 (0.04–0.11) | <0.001 |
| LASct (%) | 1.27(1.10–1.46) | 0.001 | ||
| Change in LASr | 0.47(0.29–0.75) | 0.002 | ||
| Change in LAScd | 1.17(1.09–1.25) | <0.001 | ||
| Change in LASct | 1.07 (1.00–1.15) | 0.04 | ||