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. 2025 Aug 20;16(36):16970–16978. doi: 10.1039/d5sc05902j

Table 1. Structure of amidinopeptides and folded controls.

graphic file with name d5sc05902j-u1.jpg
Peptide Amidine sequencea
Orientation Strand Turn Strand
YKL RYVEV pG OKILQ
1-Tyr(NH)2 ‘Out’ RY(NH)VEV pG OKILQ
2-Val(NH)3 ‘In’ RYV(NH)EV pG OKILQ
3-Glu(NH)4 ‘Out’ RYVE(NH)V pG OKILQ
4-Gly(NH)7 ‘Out’ RYVEV pG(NH) OKILQ
5-Orn(NH)8 ‘In’ RYVEV pG O(NH)KILQ
6-Ile(NH)10 ‘In’ RYVEV pG OKI(NH)LQ
7 RYVEV PG OKILQ
8b graphic file with name d5sc05902j-u2.jpg
a

All peptides except 8 are capped at the N-terminus with Ac and have a C-terminal amide (–CONH2).

b

Head-to-tail cyclic peptide.