Table 3.
MOFs in Breast Cancer Diagnosis and Treatments
| Type | MOFs | Application | Ref. | |
|---|---|---|---|---|
| Treatment | Chemotherapy | UIO-66-Let/Epi@NH | Drug delivery | [122] |
| Chemotherapy | La-MOFs | Drug delivery; Targeted therapy |
[123] | |
| Microwave thermo-chemotherapy | AP@ZC-HSC@PEG@PCM-DEX | Drug delivery | [124] | |
| Chemotherapy | DOX@ZIF-8/GO-FA/CP | Drug delivery; Targeted therapy |
[125] | |
| CDT | Apt-RBC-MOF@DOX | Drug delivery; Targeted therapy |
[126] | |
| PDT | MA-HfMOF-PFP-Ni-Zn; MA-HfMOF-PFC-Ni-Zn |
PDT agent for tumor therapy | [127] | |
| PDT | Zn(II)-PPIX@UiO-66-NH2 NMOFs | Cell imaging | [128] | |
| PDT-SDT | Chl-MOF | PDT agent for tumor therapy | [129] | |
| SDT | PL-PEG-PCN | SDT agent for tumor therapy | [130] | |
| PTT | CV@Bi-TCA | PTT agent for tumor therapy | [131] | |
| chemo-photothermal-photodynamic therapy |
UiO-DOX-ICG@PDA-TF | Drug delivery; Targeted therapy |
[132] | |
| Immunotherapy | MOF@siDDR2+siITGAV | Drug delivery | [133] | |
| Immunotherapy | LYS-NP | Drug delivery | [134] | |
| Microwave thermo- immunotherapy | AlEu-MOF | MW thermotherapy-responsive pyroptosis inducers | [135] | |
| Photodynamic- immunotherapy | BMS@P/HP | Drug delivery | [136] | |
| Diagnosis | Electrochemical biosensor | PEI@CQD@Ni-MOF | The breast cancer marker HER2 detector | [137] |
| Surface plasmon resonance (SPR) | Au/UiO-66-NH2 | The breast cancer marker HER2 detector | [138] | |
| Fluorometric biosensor | 2D Zn-TCPP MOF | The breast cancer marker HER2 detector | [139] | |
| Electrochemical biosensor | MIL-156 MOF@COF | The breast cancer marker CA15-3 detector | [140] | |
| Fluorescent biosensor | La (III) -MOF and Ag NPs | The breast cancer marker miRNA-155 detector | [141] |