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. 2025 Aug 18;14(8):1079. doi: 10.3390/biology14081079
HCC hepatocellular carcinoma
LIHC liver hepatocellular carcinoma
NMIRGs nucleotide metabolism and immune-related genes
C1 cluster 1
DEGs differentially expressed genes
TMB tumor mutation burden
MSI microsatellite instability
TCGA The Cancer Genome Atlas
GEO Gene Expression Omnibus
DAVID Database for Annotation, Visualization, and Integrated Discovery
LASSO Least Absolute Shrinkage and Selection Operator
MCPcounter Microenvironment Cell Populations counter
ESTIMATE Estimation of STromal and Immune cells in MAlignant Tumor tissues using Expression data
GSEA Gene Set Enrichment Analysis
NMF Non-Negative Matrix Factorization
PFS progression-free survival
DCA Decision Curve Analysis
ROC Receiver Operating Characteristic
RAC3 receptor-associated coactivator 3
HSP90AA1 heat shock protein 90 alpha family class A member 1
BTC betacellulin
MAPT microtubule-associated protein tau
HDAC1 histone deacetylase 1
STC1 stanniocalcin-1
CHGA chromogranin A
GAL galanin and GMAP prepropeptide
GHR growth hormone receptor
PD-1 programmed cell death protein 1
CTLA-4 cytotoxic T-lymphocyte-associated protein-4
ADORA2A adenosine receptor A2a