5-ASA |
5-amino salicylic acid |
EGFR |
Epidermal growth factor receptor |
FexD |
Fexaramine D |
OCA |
Obeticholic acid |
T-βMCA |
Tauro-β-muricholic acid |
FXR |
Farnesoid X receptor |
M3R |
Muscarinic acetylcholine receptor M3 |
LCA |
Lithocholic acid |
BAs |
Bile acids |
MFB |
Metformin-butyrate |
ROS |
Reactive oxygen species |
MAMPs |
Microorganism-associated molecular patterns |
TLRs |
Toll-like receptors |
TLRs |
Through Toll-like receptors |
EMT |
Epithelial-mesenchymal transition |
CRC |
Colon cancer |
LPS |
Lipopolysaccharide |
DCA |
Deoxycholic acid |
CSCs |
Cancer stem-like cells |
ERK |
Extracellular regulated protein kinases |
MAPK |
Mitogen-activated protein kinase |
PI3K |
Phosphatidylinositol 3 kinase |
AKT |
Protein kinase B |
VE-PTP |
Vascular endothelial protein tyrosine phosphatase |
AJs |
Adhesion junctions |
(VE)-cadherin |
Vascular endothelial |
TWIST1 |
Twist-related protein 1 |
EPHA2 |
Ephrin type-A receptor 2 |
VEGF |
Vascular endothelial growth factor |
MMPs |
Matrix metalloproteinases |
TGFB |
Growth factor beta 1 |
FMO1 |
Flavin-containing monooxygenase |
TMA |
Trimethylamine |
cutC/D |
Choline TMA-lyase |
CntA/B |
L-carnitine oxygenase |
SCFAs |
Short-chain fatty acids |
TMAO |
Trimethylamine N-oxide |
GM |
Gut microbiota |