ABC |
Adenosine triphosphate-binding cassette |
ABCA1 |
ATP-binding cassette transporter A1 |
ACC |
American College of Cardiology |
ACL |
Adenosin triphosphate-citrate lyase |
AHA |
American Heart Association |
ALT |
Alanine Aminotransferase |
ApoB |
Apolipoprotein B |
ASCVD |
Atherosclerotic cardiovascular disease |
AST |
Aspartate Aminotransferase |
AUC |
Area under the curve |
BCRP |
Breast cancer-resistant protein |
BMI |
Body mass index |
BP |
Blood pressure |
CAC |
Coronary artery calcium |
CAD |
Coronary artery disease |
CK |
Creatine Kinase |
CKD |
Chronic kidney disease |
COPD |
Chronic Obstructive Pulmonary Disease |
CPIC |
Clinical Pharmacogenetics Implementation Consortium |
CVD |
Cardiovascular disease |
CYP450 |
Cytochrome P450 |
DAST |
Dietary Approaches to Stop Hypertension |
DPWG |
Dutch Pharmacogenetics Working Group |
DRESS |
Drug reaction with eosinophilia and systemic symptoms |
ESC |
European Society of Cardiology |
FDA |
Food and Drug Administration |
FH |
Familial hypercholesterolemia |
FHS |
Framingham Heart Study |
HDL |
High-density lipoprotein |
HDL-C |
High-density lipoprotein cholesterol |
HeFH |
Heterozygous familial hypercholesterolemia |
HMG-CoA |
β-hydroxy β-methylglutaryl-coenzyme A |
HoFH |
Homozygous familial hypercholesterolemia |
IBD |
Inflammatory Bowel Disease |
IDL |
Intermediate-density lipoproteins |
IMPROVE-IT |
Improved Reduction in Outcomes: Vytorin Efficacy International Trial |
KDIGO |
Kidney Disease: Improving Global Outcomes |
LDL |
Low-density lipoprotein |
LDL-C |
Low-density lipoprotein cholesterol |
LDLR |
Low-density lipoprotein receptor |
LDLRAP |
Low-density lipoprotein receptor adaptor protein |
LFTs |
Liver function tests |
LPL |
Lipoprotein lipase |
MACE |
Major Adverse Cardiovascular Events |
MI |
Myocardial infarction |
MTP |
Microsomal triglyceride transfer protein |
NICE |
National Institute for Health and Care Excellence |
NPC1L1 |
Niemann-Pick C1-like 1 |
OATP |
Organic anion-transporting polypeptide |
oxLDL |
Oxidized low-density lipoprotein |
PAD |
Peripheral arterial disease |
PCE |
Pooled Cohort Equations |
PCOS |
Polycystic ovary syndrome |
PRE-CISE-IVUS |
Plaque Regression with Cholesterol Absorption Inhibitor or Synthesis Inhibitor Evaluated by Intravascular Ultrasound |
PUFAs |
Polyunsaturated fats |
SAMS |
Statin-associated musculoskeletal symptoms |
SHARPP |
Study of Heart and Renal Protection |
SR-BI |
Scavenger receptor class B type I |
TG |
Triglycerides |
UGT |
Uridine diphosphate glucuronosyltransferases |
ULN |
Upper Limit of Normal |
VLDL |
Very-low-density lipoprotein |