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. 2025 Jul 25;15(8):1185. doi: 10.3390/life15081185
ABC Adenosine triphosphate-binding cassette
ABCA1 ATP-binding cassette transporter A1
ACC American College of Cardiology
ACL Adenosin triphosphate-citrate lyase
AHA American Heart Association
ALT Alanine Aminotransferase
ApoB Apolipoprotein B
ASCVD Atherosclerotic cardiovascular disease
AST Aspartate Aminotransferase
AUC Area under the curve
BCRP Breast cancer-resistant protein
BMI Body mass index
BP Blood pressure
CAC Coronary artery calcium
CAD Coronary artery disease
CK Creatine Kinase
CKD Chronic kidney disease
COPD Chronic Obstructive Pulmonary Disease
CPIC Clinical Pharmacogenetics Implementation Consortium
CVD Cardiovascular disease
CYP450 Cytochrome P450
DAST Dietary Approaches to Stop Hypertension
DPWG Dutch Pharmacogenetics Working Group
DRESS Drug reaction with eosinophilia and systemic symptoms
ESC European Society of Cardiology
FDA Food and Drug Administration
FH Familial hypercholesterolemia
FHS Framingham Heart Study
HDL High-density lipoprotein
HDL-C High-density lipoprotein cholesterol
HeFH Heterozygous familial hypercholesterolemia
HMG-CoA β-hydroxy β-methylglutaryl-coenzyme A
HoFH Homozygous familial hypercholesterolemia
IBD Inflammatory Bowel Disease
IDL Intermediate-density lipoproteins
IMPROVE-IT Improved Reduction in Outcomes: Vytorin Efficacy International Trial
KDIGO Kidney Disease: Improving Global Outcomes
LDL Low-density lipoprotein
LDL-C Low-density lipoprotein cholesterol
LDLR Low-density lipoprotein receptor
LDLRAP Low-density lipoprotein receptor adaptor protein
LFTs Liver function tests
LPL Lipoprotein lipase
MACE Major Adverse Cardiovascular Events
MI Myocardial infarction
MTP Microsomal triglyceride transfer protein
NICE National Institute for Health and Care Excellence
NPC1L1 Niemann-Pick C1-like 1
OATP Organic anion-transporting polypeptide
oxLDL Oxidized low-density lipoprotein
PAD Peripheral arterial disease
PCE Pooled Cohort Equations
PCOS Polycystic ovary syndrome
PRE-CISE-IVUS Plaque Regression with Cholesterol Absorption Inhibitor or Synthesis Inhibitor Evaluated by Intravascular Ultrasound
PUFAs Polyunsaturated fats
SAMS Statin-associated musculoskeletal symptoms
SHARPP Study of Heart and Renal Protection
SR-BI Scavenger receptor class B type I
TG Triglycerides
UGT Uridine diphosphate glucuronosyltransferases
ULN Upper Limit of Normal
VLDL Very-low-density lipoprotein