%fPSA	Percent free PSA
ADT	Androgen deprivation therapy
AI	Artificial intelligence
APC	Adenomatous polyposis coli
AR	Androgen receptor
AS	Active surveillance
ASCO	American Society of Clinical Oncology
ATM	Ataxia-telangiectasia mutated
AUA	American Urological Association
BCR	Biochemical relapse
BRCA	Breast cancer gene
CAPRA	Cancer of the Prostate Risk Assessment
CCP	Cell-cycle progression
CCR	Clinical cell-cycle risk
cfDNA	Cell-free DNA
CHEK2	Checkpoint kinase 2
cPSA	Complexed PSA
csPC	Clinically significant prostate cancer
CSS	Cancer-specific survival
CTCs	Circulating tumor cells
ctDNA	Circulating tumor DNA
DAPK	Death-associated protein kinase 1
DLX1	Distal-less homeobox 1
DRE	Digital rectal examination
EAU	European Association of Urology
EBRT	External beam RT
ERSPC	European Randomised Study for Screening of Prostate Cancer
FDA	Food and Drug Administration
FOXA1	Forkhead box protein A1
fPSA	Free PSA
GADD45	Growth arrest and DNA-damage-inducible α
GPS	Genomic Prostate Score
GS	Gleason score
GSTP1	Glutathione-S-transferase P1 / Glutathione-S-transferase π
HER2	Human epidermal growth factor receptor 2
HOXB13	Omeobox B13
HRR	Homologous recombination repair
iPARP	Poly-ADP ribose polymerase RASSF inhibitor
ISUP	International Society of Urological Pathology
mCRPC	Metastatic castration-resistant prostate cancer
MFS	Metastasis-free survival
MiPS	Mi Prostate Score
MLH1	MutL protein homolog 1
MMR	Mismatch repair
MpMRI	Multiparametric magnetic resonance imaging
NCCN	National Comprehensive Cancer Network
NGI	Next-generation imaging
NICE	National Institute for Health and Care Excellence
NPV	Negative predictive value
OS	Overall survival
PALB2	Partner and localizer of BRCA2
PC	Prostate cancer
PCA 3	Prostate cancer antigen 3
PHI	Prostate Health Index
PI-RADS	Prostate Imaging Reporting & Data System
PMS2	Postmeiotic segregation increased 2
PSA	Prostate-specific antigen
PSA-D	PSA density
PSMA-PET/CT	Prostate-specific membrane antigen–positron emission tomography/computed tomography
PTEN	Phosphatase and tensin homolog
QoL	Quality of life
RASSF1	Ras association domain family member 1 / Ras association domain-containing protein 1
RB1	Retinoblastoma transcriptional corepressor
RP	Radical prostatectomy
RT	Radiotherapy
RTOG	Radiation Therapy Oncology Group
RUNX3	Runt-related transcription factor 3
SEER	Surveillance, Epidemiology, and End Results
SNPs	Single-nucleotide polymorphisms
SNVs	Single-nucleotide variants
SPOP	Speckle-type POZ protein
TGFβ	Transforming growth factor β
TME	Tumor microenvironment
TMPRSS2:ERG	The fusion of the transmembrane protease serine 2 gene with the erythroblast transformation-specific-related gene
TNFRSF10c	Tumor necrosis factor receptor superfamily member 10c
tPSA	Total PSA
US	United States