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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Proposed model for NR4A1 as a nutrient sensor that plays a constitutive and ligand-induced role in preventing tissue damage. NR4A1 may also contribute to the overall health benefits of dietary polyphenolics.