ACR	American College of Rheumatology
ADL	Activities of daily living
ADAMTS	A Disintegrin and Metalloproteinase with Thrombospondin Motifs
ADME(T)	Absorption, distribution, metabolism, excretion (and toxicity)
APLAR	Asia-Pacific League of Associations for Rheumatology
BSR	British Society for Rheumatology
BMAL1	Brain and muscle Arnt-like protein-1
CAGR	Compound annual growth rate
CAPA	Canadian Arthritis Patient Alliance
Clock	Circadian locomotor output cycles kaput
Cmax	Maximum plasma concentration
COMP	Cartilage oligomeric matrix protein
CRY	Cryptochrome
COX	Cyclooxygenase
CTSMA	Connective tissue structure-modifying agent
CVD	Cardiovascular disease
CYP	Cytochrome P450
DAMPs	Damage-associated molecular patterns
DMARD	Disease-modifying antirheumatic drug
DMOAD	Disease-modifying osteoarthritis drug
ECM	Extracellular matrix
ESCEO	European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases
EULAR	The European Alliance of Associations for Rheumatology
FDA	Food and Drug Administration
FIP	International Pharmaceutical Federation
Fn-fs	Fibronectin fragments
GAIT	Glucosamine hydrochloride/chondroitin sulfate Arthritis Intervention Trial
GI	Gastrointestinal
IL-1β	Interleukin-1 beta
iPSC	Induced pluripotent stem cell
MetS	Metabolic syndrome
MMPs	Matrix metalloproteinases
MSC	Mesenchymal stem cell
MRI	Magnetic resonance imaging
NSAID	Nonsteroidal anti-inflammatory drug
OA	Osteoarthritis
OAAA	Osteoarthritis Action Alliance
OAFI	Osteoarthritis Foundation International
OAI	Osteoarthritis Initiative
OARSI	Osteoarthritis Research Society International
OTC	Over-the-counter
PALs	Physical activity levels
PCC	Patient-centered care
PER	Period
PICs	Pro-inflammatory cytokines
PRG4	Proteoglycan 4 (lubricin)
PRP	Platelet-rich plasma
PTOA	Post-traumatic osteoarthritis
RA	Rheumatoid arthritis
RCT	Randomized controlled trials
RNS	Reactive nitrogen species
ROS	Reactive oxygen species
SNRI	Serotonin-norepinephrine reuptake inhibitor
SODFs	Solid Oral Dosage Forms
SYRADOA	Symptomatic rapid-acting drugs for osteoarthritis
SYSADOA	Symptomatic slow-acting drugs for osteoarthritis
THA	Total hip arthroplasty
TKA	Total knee arthroplasty
TNF-α	Tumor necrosis factor-alpha
CTX-II	Type II collagen C telopeptides
Helix-II	Type II collagen helical
VAS	Visual Analog Scale
WOMAC	Western Ontario and McMaster Universities Osteoarthritis Index