| AP3B1 | Adaptor-related protein complex 3 subunit beta 1 |
| ASC | Apoptosis-associated speck-like protein containing CARD |
| ASCC3 | Activating signal co-integrator 1 complex subunit 3 |
| CFTR | Cystic fibrosis transmembrane conductance regulator |
| COVID-19 | Coronavirus disease 2019 |
| CoVs | Coronaviruses |
| CRP | C-reactive protein |
| CTD | C-terminal domain |
| dsRNA | Double-stranded RNA |
| E | Envelope protein |
| ERGIC | Endoplasmic reticulum–Golgi intermediate compartment |
| ERK1/2 | Extracellular signal-regulated kinases 1 and 2 |
| G3BP1 | GTPase-activating protein-binding protein 1 |
| GADD34 | Growth arrest and DNA damage-inducible 34 |
| GSDMD | Gasdermin D |
| GSK-3 | Glycogen synthase kinase- |
| HCoV | Human coronavirus |
| HDAC6 | Histone deacetylases 6 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HLA | Human leukocyte antigen |
| ICU | Intensive care unit |
| IDRs | Intrinsically disordered regions |
| IFN-1 | Type I interferon |
| IgG | Immunoglobulin G |
| IgM | Immunoglobulin M |
| IKKα | IκB kinase-α |
| IL | Interleukin |
| IMPDH2 | Inosine monophosphate dehydrogenase 2 |
| IP-10 | IFN-gamma-inducible protein 10 kD |
| IRF | Interferon regulatory factor |
| ISG15 | IFN-stimulated gene 15 |
| JAK-STAT | Janus kinase-signal transducer and activator of transcription |
| KPNA | Karyopherin alpha |
| KPNB1 | Karyopherin beta 1 |
| LKR | Linking region |
| LLPS | Liquid–liquid phase separation |
| M | Membrane protein |
| MAPK | Mitogen-activated protein kinase |
| MASP-2 | Mannan-binding lectin serine protease 2 |
| MAVS | Mitochondrial antiviral signaling |
| MDA5 | Melanoma differentiation-associated gene 5 |
| MERS-CoV | Middle East respiratory syndrome coronavirus |
| MHV | Mouse Hepatitis Virus |
| MIS-C | Multisystem inflammatory syndrome |
| N | Nucleocapsid |
| NF-κB | Nuclear factor kappa B |
| NFKB1 | NF-κB subunit 1 |
| NFKBIA | NF-κB inhibitor alpha |
| NLRP3 | NLR family pyrin domain containing-3 |
| NLRs | NOD like receptors |
| NMD | Nonsense-mediated mRNA decay |
| NOD | Nucleotide-binding oligomerization domain proteins |
| NSPs | Nonstructural proteins |
| NTD | N-terminal domain |
| ORFs | Open reading frames |
| PAMPs | Pathogen-associated molecular patterns |
| PASC | Post-acute sequelae of SARS-CoV-2 infection |
| PCT | Procalcitonin |
| PDE4 | Phosphodiesterase 4 |
| PKM | Pyruvate kinase M |
| PLpro | Papain-like protease |
| poly(I:C) | Polyinosinic: polycytidylic acid |
| PRRs | Pattern recognition receptors |
| PTX3 | Pentraxin 3 |
| RAGE | Glycation end products |
| RAN | Ras-related nuclear protein |
| RdRp | RNA polymerase |
| RIG-I | Retinoic acid-inducible gene I |
| RISC | RNA-induced silencing complex |
| RLRs | RIG-I-like receptors |
| RNAi | RNA interference |
| RNP | Ribonucleoprotein |
| S | Spike protein |
| SAA | Serum amyloid A |
| SARS-CoV-2 | Severe acute respiratory syndrome coronavirus 2 |
| SARSr-CoV | SARS-related coronavirus |
| SCAP | SREBPs cleavage-activating protein |
| SGK1 | Serum glucocorticoid regulated kinase 1 |
| SGs | Stress granules |
| siRNA | Small interfering RNAs |
| SL | Stem-loop |
| SNX8 | Sorting nexin 8 |
| SR | Ser/Arg |
| SREBPs | Sterol regulatory element-binding proteins |
| SUMO | Small ubiquitin-like modifiers |
| T1D | Type 1 diabetes |
| T2D | Type 2 diabetes |
| TBK1 | Tank-binding kinase 1 |
| TCR | T cell receptor |
| TDP-43 | Transactive response-binding protein 43 kDa |
| Th1 | T helper type 1 |
| TLR2 | Toll-like receptor 2 |
| TMAO | Trimethylamine N-oxide |
| TNF | Tumor necrosis factor |
| TNFR2 | Tumor necrosis factor receptor 2 |
| TRIM25 | Tripartite motif protein 25 |
| TRIM6 | Tripartite motif protein 6 |
| UBC9 | Ubiquitin-conjugating enzyme 9 |
| UPF1 | UP-frameshift-1 |
| VOCs | Variants of concern |
| YBX1 | Y-box binding protein 1 |