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. 2025 Jul 27;17(8):1046. doi: 10.3390/v17081046
AP3B1 Adaptor-related protein complex 3 subunit beta 1
ASC Apoptosis-associated speck-like protein containing CARD
ASCC3 Activating signal co-integrator 1 complex subunit 3
CFTR Cystic fibrosis transmembrane conductance regulator
COVID-19 Coronavirus disease 2019
CoVs Coronaviruses
CRP C-reactive protein
CTD C-terminal domain
dsRNA Double-stranded RNA
E Envelope protein
ERGIC Endoplasmic reticulum–Golgi intermediate compartment
ERK1/2 Extracellular signal-regulated kinases 1 and 2
G3BP1 GTPase-activating protein-binding protein 1
GADD34 Growth arrest and DNA damage-inducible 34
GSDMD Gasdermin D
GSK-3 Glycogen synthase kinase-
HCoV Human coronavirus
HDAC6 Histone deacetylases 6
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HLA Human leukocyte antigen
ICU Intensive care unit
IDRs Intrinsically disordered regions
IFN-1 Type I interferon
IgG Immunoglobulin G
IgM Immunoglobulin M
IKKα IκB kinase-α
IL Interleukin
IMPDH2 Inosine monophosphate dehydrogenase 2
IP-10 IFN-gamma-inducible protein 10 kD
IRF Interferon regulatory factor
ISG15 IFN-stimulated gene 15
JAK-STAT Janus kinase-signal transducer and activator of transcription
KPNA Karyopherin alpha
KPNB1 Karyopherin beta 1
LKR Linking region
LLPS Liquid–liquid phase separation
M Membrane protein
MAPK Mitogen-activated protein kinase
MASP-2 Mannan-binding lectin serine protease 2
MAVS Mitochondrial antiviral signaling
MDA5 Melanoma differentiation-associated gene 5
MERS-CoV Middle East respiratory syndrome coronavirus
MHV Mouse Hepatitis Virus
MIS-C Multisystem inflammatory syndrome
N Nucleocapsid
NF-κB Nuclear factor kappa B
NFKB1 NF-κB subunit 1
NFKBIA NF-κB inhibitor alpha
NLRP3 NLR family pyrin domain containing-3
NLRs NOD like receptors
NMD Nonsense-mediated mRNA decay
NOD Nucleotide-binding oligomerization domain proteins
NSPs Nonstructural proteins
NTD N-terminal domain
ORFs Open reading frames
PAMPs Pathogen-associated molecular patterns
PASC Post-acute sequelae of SARS-CoV-2 infection
PCT Procalcitonin
PDE4 Phosphodiesterase 4
PKM Pyruvate kinase M
PLpro Papain-like protease
poly(I:C) Polyinosinic: polycytidylic acid
PRRs Pattern recognition receptors
PTX3 Pentraxin 3
RAGE Glycation end products
RAN Ras-related nuclear protein
RdRp RNA polymerase
RIG-I Retinoic acid-inducible gene I
RISC RNA-induced silencing complex
RLRs RIG-I-like receptors
RNAi RNA interference
RNP Ribonucleoprotein
S Spike protein
SAA Serum amyloid A
SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2
SARSr-CoV SARS-related coronavirus
SCAP SREBPs cleavage-activating protein
SGK1 Serum glucocorticoid regulated kinase 1
SGs Stress granules
siRNA Small interfering RNAs
SL Stem-loop
SNX8 Sorting nexin 8
SR Ser/Arg
SREBPs Sterol regulatory element-binding proteins
SUMO Small ubiquitin-like modifiers
T1D Type 1 diabetes
T2D Type 2 diabetes
TBK1 Tank-binding kinase 1
TCR T cell receptor
TDP-43 Transactive response-binding protein 43 kDa
Th1 T helper type 1
TLR2 Toll-like receptor 2
TMAO Trimethylamine N-oxide
TNF Tumor necrosis factor
TNFR2 Tumor necrosis factor receptor 2
TRIM25 Tripartite motif protein 25
TRIM6 Tripartite motif protein 6
UBC9 Ubiquitin-conjugating enzyme 9
UPF1 UP-frameshift-1
VOCs Variants of concern
YBX1 Y-box binding protein 1