Skip to main content
. 2025 Jul 29;17(7):e88954. doi: 10.7759/cureus.88954

Table 2. Change in SBP and DBP from baseline to follow-up.

DBP: diastolic blood pressure, SBP: systolic blood pressure, SD: standard deviation.

*Paired t-test was used to test if there is a significant change in means from baseline to follow-up visits.

Parameters SBP, mean ± SD DBP, mean ± SD
  Visit 1 Visit 2 Change T-value P-value* Visit 1 Visit 2 Change T-value P-value*
Amlodipine (n=2460) 158.6 ± 17.3 140.8 ± 16.2 -17.8 ± 19.6 45.15 <0.001 95.0 ± 8.4 85.4 ± 9.2 -9.5 ± 10.7 44.37 <0.001
Amlodipine+ telmisartan (n=2847) 161.0 ± 16.9 139.4 ± 16.6 -21.6 ± 19.2 60.25 <0.001 95.8 ± 8.3 84.4 ± 9.0 -11.4 ± 10.2 59.55 <0.001
Amlodipine+ atenolol (n=477) 159.5 ± 18.1 138.2 ± 17.2 -21.3 ± 21.1 22.1 <0.001 95.3 ± 8.7 83.6 ± 9.4 -11.7 ± 11.5 22.36 <0.001
Amlodipine+ bisoprolol (n=639) 161.6 ± 17.8 137.9 ± 16.1 -23.6 ± 19.0 31.4 <0.001 96.3 ± 8.7 83.4 ± 9.3 -12.8 ± 10.5 31.04 <0.001
Amlodipine+ metoprolol (n=1356) 160.6 ± 17.1 140.7 ± 16.8 -19.8 ± 19.7 37.14 <0.001 95.9 ± 8.7 85.5 ± 9.3 -10.4 ± 10.6 35.84 <0.001
Amlodipine+ chlorthalidone+ telmisartan (n=429) 163.0 ± 17.3 137.8 ± 16.0 -25.2 ± 20.9 24.92 <0.001 96.0 ± 8.6 83.2 ± 8.9 -12.7 ± 10.9 24.22 <0.001
Amlodipine+ hydrochlorothiazide+ telmisartan (n=1557) 163.2 ± 17.2 139.7 ± 16.8 -23.4 ± 19.9 46.42 <0.001 96.6 ± 9.1 84.6 ± 9.2 -12.0 ± 10.6 44.48 <0.001
Amlodipine+ hydrochlorothiazide+ olmesartan (n=429) 166.3 ± 17.4 141.4 ± 17.8 -24.9 ± 20.5 25.2 <0.001 98.0 ± 8.9 85.1 ± 9.4 -12.9 ± 11.1 24.23 <0.001