Table 1.

Sensitivity analyses association between CCR and mortality using different censor strategies.

Exposure	Model 1a N = 3,177 HR (95% CI) p-value	Model 2b N = 3,088 HR (95% CI) p-value	Model 3c N = 2,946 HR (95% CI) p-value
Censored at 1 year
CCR categorical
≤80 (ml/min)	Reference	Reference	Reference
>80, ≤120 (ml/min)	0.30 (0.17, 0.53) < 0.01	0.30 (0.17, 0.54) < 0.01	0.45 (0.24, 0.85) 0.01
>120 (ml/min)	0.11 (0.03, 0.44) < 0.01	0.11 (0.03, 0.44) < 0.01	0.19 (0.04, 0.78) 0.02
CCR continuous (ml/min)	0.97 (0.96, 0.98) < 0.01	0.97 (0.96, 0.98) < 0.01	0.98 (0.97, 0.99) < 0.01
Censored at 2 years
CCR categorical
≤80 (ml/min)	Reference	Reference	Reference
>80, ≤120 (ml/min)	0.35 (0.23, 0.54) < 0.01	0.35 (0.22, 0.54) < 0.01	0.56 (0.35, 0.89) 0.01
>120 (ml/min)	0.10 (0.03, 0.32) < 0.01	0.10 (0.03, 0.32) < 0.01	0.19 (0.06, 0.60) < 0.01
CCR continuous (ml/min)	0.97 (0.97, 0.98) < 0.01	0.97 (0.96, 0.98) < 0.01	0.98 (0.97, 0.99) < 0.01
Censored at 3 years
CCR categorical
≤80 (ml/min)	Reference	Reference	Reference
>80, ≤120 (ml/min)	0.35 (0.24, 0.52) < 0.01	0.35 (0.24, 0.52) < 0.01	0.52 (0.35, 0.79) < 0.01
>120 (ml/min)	0.11 (0.04, 0.30) < 0.01	0.11 (0.04, 0.30) < 0.01	0.18 (0.07, 0.50) < 0.01
CCR continuous (ml/min)	0.97 (0.97, 0.98) < 0.01	0.97 (0.97, 0.98) < 0.01	0.98 (0.97, 0.99) < 0.01

^aNo adjustment.

^bAdjusted for PT, APTT, platelet, hemoglobin, albumin, calcium, neutrophils, lymphocytes, monocytes, and potassium.

^cAdjusted for PT, APTT, platelet, hemoglobin, albumin, calcium, neutrophils, lymphocytes, monocytes, potassium, uric acid, ASA category, hypertension, diabetes, tumor, shock, and smoking.