[Preprint]. 2025 Aug 22:2025.08.18.670886. [Version 1] doi: 10.1101/2025.08.18.670886

Table 4.

Definition of model parameters that are randomly altered to introduce variability into the population of models.

Model Parameters used in Sensitivity Analysis
G _Na		Na⁺ current, maximum conductance
G _K1		Inward rectifying K⁺ current, maximum conductance
G _Kur		Ultra-rapid rectifying K⁺ current, maximum conductance
G _KAch		Acetylcholine-sensitive K⁺ current, maximum conductance
G _to,f		Transient outward K⁺ current, fast component, maximum conductance
CSQ		Calsequestrin expression
V _NaK		Na⁺/K⁺ ATPase current, maximum velocity
G _KCa		SK current, maximum conductance
G _NaL		Late Na⁺ current, maximum conductance
G _Kr		Rapid delayed rectifying K⁺ current, maximum conductance
G _Ks		Slow delayed rectifying K⁺ current, maximum conductance
G _K2P		K2P current, maximum conductance
L-Type	K1o	L-type Ca²⁺ current inactivation rate constant
	CaMKII-p	CaMKII-phosphorylation of L-type Ca²⁺ current
	G _CaL	L-type Ca²⁺ current, maximum conductance
V _NCX		Na⁺/Ca²⁺ exchange current, maximum velocity
Kmf		SERCA sensitivity to [Ca²⁺]_Cyto
RyR	EC50	Concentration of Ca²⁺ that induces half maximum Po
	V _RyR	Ryanodine receptor flux, maximum velocity
	K _leak	Ryanodine receptor Ca²⁺ leak, maximum velocity
	KoCa	Activation rate constant for RyR
	KiCa	Inactivation rate constant for RyR
	Kim	Transition rate constant for RyR
	Kom	Transition rate constant for RyR
G _CaB		Background Ca²⁺ current, maximum conductance
G _ClB		Background Cl⁻ current, maximum conductance
G _ClCa		Ca²⁺-activated Cl⁻ current, maximum conductance
G _NaB		Background Na⁺ current, maximum conductance
G _Kp		Plateau K⁺ current, maximum conductance
V _SERCA		Sarcoplasmic reticulum Ca²⁺ ATPase flux, maximum velocity
V _PMCA		Plasma membrane Ca²⁺ ATPase current, maximum velocity
Ca²⁺ Buffer Cleft		Ca²⁺ buffering strength in the cleft space
Ca²⁺ Buffer Cytosol		Ca²⁺ buffering strength in the cytosolic space