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. 2025 Jul 29;17(7):e89022. doi: 10.7759/cureus.89022

Table 2. Histopathological characteristics of tumors in patients with non–clear cell renal cell carcinoma (nccRCC).

Rare variants included tubulocystic RCC, medullary carcinoma, and MiT family translocation RCC.

RCC: Renal cell carcinoma; G: Grade (Fuhrman nuclear grade); T: Tumor stage (AJCC 8th edition).

Variable Frequency (%) / Mean ± SD
Subtypes  
Papillary RCC 14 (37.8%)
Chromophobe RCC 8 (21.6%)
Collecting duct carcinoma 5 (13.5%)
Xp11.2 translocation RCC 2 (5.4%)
Mucinous tubular and spindle cell 2 (5.4%)
Unclassified RCC 3 (8.1%)
Other rare variants 3 (8.1%)
Tumor size (cm) 6.8 ± 2.5
Tumor size category  
< 4 cm 6 (16.2%)
4–7 cm 17 (45.9%)
> 7 cm 14 (37.8%)
Histological grade (Fuhrman)  
G1–2 18 (48.6%)
G3–4 19 (51.4%)
Pathological T stage  
T1 14 (37.8%)
T2 5 (13.5%)
T3–T4 18 (48.6%)
Lymphovascular invasion 10 (27.0%)
Sarcomatoid differentiation 5 (13.5%)
Tumor necrosis 12 (32.4%)