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. 2025 Aug 18;30:629–640. doi: 10.1016/j.reth.2025.08.003

Table 2.

Modified Allred scoring system. The modified Allred Score system was used to analyze immunohistochemical staining of CD31 and alpha-smooth muscle actin (α-SMA) markers, and they were scored based on the Proportion and intensity of staining.

Proportion score (P) Intensity score (I) Allred score (P + I)
No cells are immunoreactive = 0 Negative = 0 Negative = 0-1
≤1 % of cells are immunoreactive = 1 Weak = 1 Weak = 2-3
1–10 % of cells are immunoreactive = 2 Intermediate = 2 Moderate = 4-6
11–33 % of cells are immunoreactive = 3 Strong = 3 Strong = 7-8
34–66 % of cells are immunoreactive = 4
67–100 % of cells are immunoreactive = 5