Table 2.

Propofol plasma concentrations measured in 2023 and in 2015.

Sample	Patient #1			Patient #2			Patient #3			Patient #4			Patient #5
	C 2015 (μg/mL)	C 2023 (μg/mL)	% RE	C 2015 (μg/mL)	C 2023 (μg/mL)	% RE	C 2015 (μg/mL)	C 2023 (μg/mL)	% RE	C 2015 (μg/mL)	C 2023 (μg/mL)	% RE	C 2015 (μg/mL)	C 2023 (μg/mL)	% RE
1	8.54	7.57	−11.4	7.01	6.99	−0.2	4.95	3.97	−20	7.29	7.30	0.2	6.07	7.76	27.8
2	9.00	8.28	−8.0	6.35	7.17	13.0	2.76	2.19	−21	1.58	1.59	0.9	2.28	1.80	−20.9
3	8.84	7.67	−13.2	7.19	7.07	−1.7	3.27	2.20	−33	2.79	1.87	−33.1	3.26	2.32	−28.8
4	1.80	1.58	−12.1	2.66	2.72	2.1	4.18	3.30	−21	2.71	2.83	4.3	3.11	2.00	−35.9
5	3.26	2.85	−12.6	1.36	1.40	2.6	4.19	3.37	−20	7.09	5.95	−16.1	9.53	7.33	−23.1
6	3.55	3.30	−7.0	2.40	2.53	5.4	4.61	3.99	−13	5.88	5.14	−12.6	6.63	3.22	−51.4
7	3.52	3.21	−8.9	2.46	2.60	5.5	6.45	5.30	−18	4.64	4.28	−7.8	6.86	6.45	−5.9
8	2.66	3.64	36.9	6.67	7.03	5.4	3.26	2.68	−18	7.46	6.89	−7.6	3.13	3.62	15.7
9	3.19	4.66	46.2	5.67	5.99	5.6	3.36	2.60	−23	7.88	7.67	−2.7	2.35	2.23	−5.3
10	3.02	4.35	44.1	5.13	5.36	4.5	2.87	1.99	−31	1.70	2.06	21.4	3.00	2.22	−26.0
11	2.70	3.63	34.5	5.22	5.03	−3.7	2.88	1.59	−45	0.38	0.40	5.8	2.02	1.51	−25.5
12	1.67	1.65	−1.4	2.22	2.36	6.1	0.82	0.51	−38				0.47	0.40	−15.3
13	1.76	1.63	−7.6	1.84	1.94	5.2
14	0.90	1.19	32.4	1.63	1.85	13.6
15	0.86	1.08	25.1	1.03	1.08	5.2
16	0.26	0.21	−20.6	0.45	0.46	1.6
Median			−7.3			5.2			−20.8			−2.7			−22.0
Q25			−11.6			2.0			−31.2			−0.2			−26.7
Q75			32.9			5.5			−9.1			2.6			−5.8

Note: %RE, relative deviation; Q25, 25% quantile; Q75, 75% quantile.