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. 1996 Sep;46(410):529–532.

A confidential enquiry into deaths caused by asthma in an English health region: implications for general practice.

G Mohan 1, B D Harrison 1, R M Badminton 1, S Mildenhall 1, N J Wareham 1
PMCID: PMC1239748  PMID: 8917872

Abstract

AIM: To determine the factors contributing to death from asthma in patients aged under 65 years in East Anglia in the early 1990s. METHOD: We have performed on ongoing confidential enquiry since January 1992. For the first time a general practitioner was included in the enquiry team. RESULTS: A review of the clinical and pathological data of the 50 patients reported in the first 3 years suggested that 36 of these deaths were attributable to asthma. Thirty-one patients died out of hospital (3 en route to the hospital), 2 in the Accident and Emergency department, and only 3 in hospital. Adverse social factors were found in 25 out of 34 patients, and adverse psychological characteristics in 23 of the 31 patients where these could be assessed. Only 7 appeared to have no adverse psychological or social factors. Routine medical care was considered appropriate in 20 patients, and inappropriate in 14. Twenty-four had received appropriate advice and education. Nine of the 21 patients, where this could be assessed, and half the relatives, failed to respond appropriately to worsening asthma symptoms during the fatal attack. No potentially preventable factors were identified in two women who died of end stage asthma. CONCLUSION: This enquiry has demonstrated that inadequacies in the medical care of asthma continue to occur, although less frequently than in previous asthma-death studies. In addition, 79% of the patients had experienced psychosocial factors which appeared important in contributing to their deaths. Recommendations for identifying and managing such "at risk' patients have been circulated to all general practitioners and chest physicians in the region.

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Selected References

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  1. Campbell D. A., McLennan G., Coates J. R., Frith P. A., Gluyas P. A., Latimer K. M., Luke C. G., Martin A. J., Roder D. M., Ruffin R. E. A comparison of asthma deaths and near-fatal asthma attacks in South Australia. Eur Respir J. 1994 Mar;7(3):490–497. doi: 10.1183/09031936.94.07030490. [DOI] [PubMed] [Google Scholar]
  2. Campbell D. A., Yellowlees P. M., McLennan G., Coates J. R., Frith P. A., Gluyas P. A., Latimer K. M., Luke C. G., Martin A. J., Ruffin R. E. Psychiatric and medical features of near fatal asthma. Thorax. 1995 Mar;50(3):254–259. doi: 10.1136/thx.50.3.254. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Crane J., Pearce N., Burgess C., Woodman K., Robson B., Beasley R. Markers of risk of asthma death or readmission in the 12 months following a hospital admission for asthma. Int J Epidemiol. 1992 Aug;21(4):737–744. doi: 10.1093/ije/21.4.737. [DOI] [PubMed] [Google Scholar]
  4. Ehrlich R. I., Bourne D. E. Asthma deaths among coloured and white South Africans: 1962 to 1988. Respir Med. 1994 Mar;88(3):195–202. doi: 10.1016/s0954-6111(05)80347-6. [DOI] [PubMed] [Google Scholar]
  5. Harrison B. D., Pearson M. G. Audit in acute severe asthma--who benefits? J R Coll Physicians Lond. 1993 Oct;27(4):387–390. [PMC free article] [PubMed] [Google Scholar]
  6. Lang D. M., Polansky M. Patterns of asthma mortality in Philadelphia from 1969 to 1991. N Engl J Med. 1994 Dec 8;331(23):1542–1546. doi: 10.1056/NEJM199412083312302. [DOI] [PubMed] [Google Scholar]
  7. Molfino N. A., Nannini L. J., Rebuck A. S., Slutsky A. S. The fatality-prone asthmatic patient. Follow-up study after near-fatal attacks. Chest. 1992 Mar;101(3):621–623. doi: 10.1378/chest.101.3.621. [DOI] [PubMed] [Google Scholar]
  8. Rea H. H., Scragg R., Jackson R., Beaglehole R., Fenwick J., Sutherland D. C. A case-control study of deaths from asthma. Thorax. 1986 Nov;41(11):833–839. doi: 10.1136/thx.41.11.833. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Robertson C. F., Rubinfeld A. R., Bowes G. Deaths from asthma in Victoria: a 12-month survey. Med J Aust. 1990 May 21;152(10):511–517. doi: 10.5694/j.1326-5377.1990.tb125350.x. [DOI] [PubMed] [Google Scholar]
  10. Sears M. R., Rea H. H., Beaglehole R., Gillies A. J., Holst P. E., O'Donnell T. V., Rothwell R. P., Sutherland D. C. Asthma mortality in New Zealand: a two year national study. N Z Med J. 1985 Apr 24;98(777):271–275. [PubMed] [Google Scholar]
  11. Strunk R. C., Mrazek D. A., Fuhrmann G. S., LaBrecque J. F. Physiologic and psychological characteristics associated with deaths due to asthma in childhood. A case-controlled study. JAMA. 1985 Sep 6;254(9):1193–1198. [PubMed] [Google Scholar]
  12. Wareham N. J., Harrison B. D., Jenkins P. F., Nicholls J., Stableforth D. E. A district confidential enquiry into deaths due to asthma. Thorax. 1993 Nov;48(11):1117–1120. doi: 10.1136/thx.48.11.1117. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Yellowlees P. M., Ruffin R. E. Psychological defenses and coping styles in patients following a life-threatening attack of asthma. Chest. 1989 Jun;95(6):1298–1303. doi: 10.1378/chest.95.6.1298. [DOI] [PubMed] [Google Scholar]

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