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. 2005 Oct 4;3(11):e343. doi: 10.1371/journal.pbio.0030343

Figure 3. Distribution of Normalized Z Scores of Three-Node Network Motifs (Left), and Z Scores Classified by Stability within Specific Density Groups (Right).

Figure 3

(Top panel, left) All 13 network motifs are sorted on the x-axis first, according to increasing number of edges (solid red line). For a given number of edges, they are then sorted from high to low SSS (black bars).

(Bottom five panels, left) Normalized Z scores (green bars) for all 13 motifs of the transcriptional networks of E. coli and S. cerevisiae, STKE network, D. melanogaster developmental transcriptional network, and C. elegans neuronal network, shown with outlines of the SSS from the top panel (dotted black outline provided as a guide to the eye). Each vertical red line indicates a change in the number of motif edges, indicating boundaries of density groups.

(Right) Z scores of network motifs in the three-edge and four-edge density groups are plotted in columns labeled I, II, and III, corresponding to the three stability classes, SSS = 1, SSS ≈ 0.4, and SSS < 0.2, respectively. Note that the four-edge density group does not contain any motifs with SSS = 1 since four edges among three nodes dictates at least one feedback loop.