Table 4.
Protective efficacy of IPTi by season of administration in 2-12 month old infants. Values are percentages (95% confidence intervals)
| Doses administered | No of children | All episodes of malaria* | Malaria episodes with parasite ≥5000/μl* | Anaemia (PCV<24) | Hospital admissions for malaria |
|---|---|---|---|---|---|
| 1, 2, and 3 in dry season | 524 | 24 (−7 to 46) | 31 (−6 to 55) | 44 (−122 to 86) | 61 (−91 to 7) |
| 1 in wet, 2 and 3 in dry | 363 | 2 (−54 to 37) | −13 (−103 to 38) | 67 (−216 to 97) | − |
| 2 in wet, 1 and 3 in dry | 366 | 37 (10 to 56) | 24 (−22 to 52) | 17 (−232 to 79) | −105 (−958 to 60) |
| 3 in wet, 1 and 2 in dry | 1901 | 15 (−1 to 28) | 17 (−2 to 33) | 29 (−31 to 62) | 43 (−5 to 69) |
| 1 and 2 in wet, 3 in dry | 965 | 52 (37 to 63) | 57 (38 to 70) | 72 (12 to 91) | 57 (−135 to 92) |
| 1 and 3, 2 and 3, or all three in wet | 112 | 28 (−40 to 63) | 24 (−73 to 67) | 28 (−1046 to 4) | − |
| 1, 2, and 3 in any season | 2098 | 27 (16 to 37) | 28 (14 to 39) | 43 (11 to 64) | 44 (8 to 66) |
PCV=packed cell volume.
*
Up to 28 days person time at risk and any episodes excluded after treatment with chloroquine or other antimalarial agent.