FIG. 2.

Phylogenetic tree of haloalkane dehalogenases and epoxide hydrolases. The sequence designations for haloalkane dehalogenases are shown in Table 1, and the sequence designations for epoxidases are as follows: Hyes_human, soluble epoxide hydrolase from Homo sapiens; Hyep_human, microsomal epoxide hydrolase from H. sapiens; Hyep_rat, microsomal epoxide hydrolase from rat; Hyes_mouse, soluble epoxide hydrolase from mouse; Hyes_rat, soluble epoxide hydrolase from rat; Hyep_rabit, microsomal epoxide hydrolase from rabbit; and Stu02494, epoxide hydrolase from Solanum tuberosum. The sequences used for fingerprinting of epoxide hydralases were obtained from the Protein Motif Fingerprint Database (3). The numbers at the nodes are the confidence values for the groups derived from 1,000 rounds of the bootstrap procedure.