Figure 5.
Medial prefrontal cortex exerts control on the striatum in explicit learning condition. (Right panel) Psychophysiological interaction analysis showing medial prefrontal area [-10 46 20 mm] in which rCBF correlation with caudate nucleus activity is modulated by the RSI condition [RSI0 vs. RSI250] under Exclusion instructions (psvc < 0.05). Data are displayed at the uncorrected p < 0.001 threshold on averaged T-1-weighted MRI. (Left panel) Scatterplot of the correlations between rCBF changes in the medial prefrontal cortex and the caudate nucleus in RSI0 (circles, gray regression line) and RSI250 (crosses, black regression line) conditions under the Exclusion instruction. Activity of these two regions is coupled in the RSI250 condition only.